Leah Pandiscia, PhD
July 28, 2017
In this study, the toxic mechanism and effects of perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHS), and perfluorobutane sulfonate (PFBS) were… Continue reading Interaction rule and mechanism of perfluoroalkyl sulfonates containing different carbon chains with human serum albumin
Leah Pandiscia, PhD
July 28, 2017
A cholesteryloxyallene (1) bearing chiral cholesteryl pendant group was designed and synthesized. Living polymerization of this monomer with an allylnickel… Continue reading Synthesis and chiroptical properties of helical polyallenes bearing chiral cholesteryl pendant groups
Leah Pandiscia, PhD
July 28, 2017
G-rich and C-rich DNA can fold into the tetrastranded helical structures G-quadruplex or C-quadruplex (i-motif) that are considered as specific… Continue reading Porphyrin Bound to i-motifs: Intercalation versus External Groove Binding
Leah Pandiscia, PhD
July 28, 2017
Oxalate oxidase is a manganese containing enzyme that catalyzes the oxidation of oxalate to carbon dioxide in a reaction that… Continue reading Hydrogen peroxide inhibition of bicupin oxalate oxidase
Leah Pandiscia, PhD
July 28, 2017
The cyclic lipopeptide surfactin (SF) is one of the promising environmental friendly biosurfactants abundantly produced by microorganisms such as Bacillus subtilis.… Continue reading pH-induced conformational change of natural cyclic lipopeptide surfactin and the effect on protease activity
Leah Pandiscia, PhD
July 28, 2017
Yersinia pestis (Y. pestis) has caused an alarming number of deaths throughout recorded human history, and novel prophylactics and therapeutics are necessary… Continue reading Identification and characterization of a neutralizing monoclonal antibody that provides complete protection against Yersinia pestis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Far-UV Circular Dichroism experiments and Atomic Force Microscopy tomography are employed to assess the impact of β-sheet breakers on the… Continue reading The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process
Leah Pandiscia, PhD
July 28, 2017
Luminescent chiral europium(III) complexes EuLRCl3 (1) and EuLSCl3 (2) were synthesised [where LR and LS are schiff-base ligands of 2,9-dialdehyde 1,10-phenanthroline and (R) and (S) isomer… Continue reading Synthesis, characterization and photo-physical properties of Eu(III) complexes and its luminescent thin films
Leah Pandiscia, PhD
July 28, 2017
The formation and deposition of amyloid fibrils have been linked to the pathogenesis of numerous debilitating neurodegenerative disorders. Serum albumins… Continue reading Inhibition of HSA Fibrillation by Two Dimensional Nanoparticles
Leah Pandiscia, PhD
July 28, 2017
The jam-packed intracellular environments differ the activity of a biological macromolecule from that in laboratory environments (in vitro) through a… Continue reading Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding
Leah Pandiscia, PhD
July 28, 2017
Telomeric repeat-containing RNA is a new non-coding RNA molecule that performs various bio-functions. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an… Continue reading Structure-dependent binding of hnRNP A1 to telomere RNA
Leah Pandiscia, PhD
July 28, 2017
Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of… Continue reading Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A CuAu38 bimetallic nanocluster was synthesized by adding a single copper atom to the Au38(2-PET)24 nanocluster. The absence of CuxAu38(2-PET)24… Continue reading Au38Cu1(2-PET)24 Nanocluster : Synthesis, Enantioseparation and Luminescence
Leah Pandiscia, PhD
July 28, 2017
1-Methoxy-8-(diphenylphosphino)triptycene (1), featuring high structural rigidity and steric bulkiness around the phosphine functionality, was synthesized as a new chiral monophosphine… Continue reading Synthesis and Catalytic Applications of a Triptycene-Based Monophosphine Ligand for Palladium-Mediated Organic Transformations
Leah Pandiscia, PhD
July 28, 2017
Near-infrared (NIR) fluorescent proteins (FPs) designed from PAS (Per-ARNT-Sim repeats) and GAF (cGMP phosphodiesterase/adenylate cyclase/FhlA transcriptional activator) domains of bacterial… Continue reading Interaction of Biliverdin Chromophore with Near-Infrared Fluorescent Protein BphP1-FP Engineered from Bacterial Phytochrome
Leah Pandiscia, PhD
July 28, 2017
Engineering of molecular stacking arrangement via environmental stimuli is of particular interest in stimuli-responsive self-assembling architectures. A novel dual photo-functionalized… Continue reading Mesomorphism, polymerization, and chirality induction in α-cyanostilbene-functionalized diacetylene-assembled films: Photo-triggered Z/E isomerization
Leah Pandiscia, PhD
July 28, 2017