The function of xanthophylls in the organisation and structure of the photosynthetic complexes is not completely clarified yet. Recently, we… Continue reading Zeaxanthin and echinenone modify the structure of photosystem I trimer in Synechocystis sp. PCC 6803
Leah Pandiscia, PhD
July 28, 2017
Low transfection efficiency and high cytotoxicity of polymeric gene carriers have hampered the application of numerous polycations for gene therapy.… Continue reading A smart gene delivery platform: Cationic oligomer
Leah Pandiscia, PhD
July 28, 2017
Circularly polarized light (CPL), regarded as a true chiral entity, has been suggested as one possible origin of the homochirality… Continue reading Chiral induction, transfer and modulation in C3-symmetric Columnar Liquid Crystalline Assemblies
Leah Pandiscia, PhD
May 24, 2018
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Seven new alkaloids belonging to three typical classes, isolated from an ethanolic extract of Pandanus amaryllifolius, were applied to establish the… Continue reading Isolation and absolute configuration determination of alkaloids from Pandanus amaryllifolius
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The design and development of vaccines, which can induce cellular immunity, particularly CD8+ T cells hold great importance since these… Continue reading A Modular Antigen Presenting Peptide/Oligonucleotide Nanostructure Platform for Inducing Potent Immune Response
Leah Pandiscia, PhD
July 28, 2017
Perturbations in protein structure define the mechanism of allosteric regulation and biological information transfer. In cytochrome c (cyt c), Met80… Continue reading Remote Perturbations in Tertiary Contacts Trigger Lysine Ligation to the Heme Iron in Cytochrome c
Leah Pandiscia, PhD
July 28, 2017
A water-stable metal-organic framework (MOF) [(PCN-333(Fe)] with ultra-large cavities and ultra-high porosity was synthesized, and employed to encapsulate horseradish peroxidases… Continue reading Encapsulation of enzyme into mesoporous cages of metal-organic frameworks for the development of highly stable electrochemical biosensors
Leah Pandiscia, PhD
July 28, 2017
Effective control of endotoxins and bacteria is crucial for normal wound healing. During injury, the key enzyme thrombin is formed,… Continue reading Aggregation of thrombin-derived C-terminal fragments as a previously undisclosed host defense mechanism
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Amyloidogenic proteins often form many types of aggregates, which are a critical determinant of cytotoxicity and tissue specificity. However, the… Continue reading Kinetics and polymorphs of yeast prion Sup35NM amyloidogenesis
Leah Pandiscia, PhD
July 28, 2017
In this report, a novel silk fibroin hydrogel with a reversible sol–gel transition capacity is presented, in which the base… Continue reading A silk fibroin hydrogel with reversible sol–gel transition
Leah Pandiscia, PhD
July 28, 2017
Myosin storage myopathy (MSM) is a congenital myopathy characterized by the presence of subsarcolemmal inclusions of myosin in the majority… Continue reading Mutations in the β-myosin rod cause myosin storage myopathy via multiple mechanisms
Leah Pandiscia, PhD
July 28, 2017
Falcipain-2 (FP2), the major cysteine protease of the human malaria parasite Plasmodium falciparum, is a hemoglobinase and promising drug target.… Continue reading Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease
Leah Pandiscia, PhD
July 28, 2017
Protein conformational diseases, including Alzheimer’s, Huntington’s, and Parkinson’s diseases, result from protein misfolding, giving a distinct fibrillar feature termed amyloid.… Continue reading Amyloid ion channels: A common structural link for protein-misfolding disease
Leah Pandiscia, PhD
July 28, 2017
Since the process of insulin fibril assembly is linked to a multitude of medical problems, finding effective and biocompatible inhibitors… Continue reading Uniform, polycrystalline and thermostable piperine-coated gold nanoparticles to target insulin fibril assembly
Leah Pandiscia, PhD
July 28, 2017
Collagen from three different sources has been added to a tung oil-based thermosetting resin in order to enhance its mechanical… Continue reading Biocomposites from the Reinforcement of a Tung Oil-based Thermosetting Resin with Collagen
Leah Pandiscia, PhD
July 28, 2017
Herein, enantiomeric polylactide-containing chiral block copolymers (BCPs*) with aliphatic and aromatic junctions are designed and synthesized for investigating the impact… Continue reading Competitive Interactions of π-π Junctions and their Role on Microphase Separation of Chiral Block Copolymers
Leah Pandiscia, PhD
July 28, 2017