Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
We have investigated the electrostatic interaction between bare iron oxide nanoparticles (IONPs) or low molecular weight chitosan coated iron oxide… Continue reading Assessing safety and protein interactions of surface-modified iron oxide nanoparticles for potential use in biomedical areas
Leah Pandiscia, PhD
July 28, 2017
We synthesized rationally designed multifunctional nanoparticles (NPs) composed of a superparamagnetic iron oxide nanoparticle (SPION) core, cyanine fluorescent dye emitting… Continue reading Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Investigations into the immunological response of proteins is often masked by lipopolysaccharide (LPS) contamination. We report an optimized Triton X-114… Continue reading Optimized Triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins
Leah Pandiscia, PhD
July 28, 2017
The deposition of human islet amyloid polypeptide (hIAPP) is closely correlated with type II diabetes mellitus (T2DM). hIAPP misfolding, as… Continue reading Binuclear ruthenium complexes inhibit the fibril formation of human islet amyloid polypeptide
Leah Pandiscia, PhD
July 28, 2017
Peptides derived from the C-terminal heptad repeat (CHR) region of the HIV-1 fusogenic protein gp41 are potent viral entry inhibitors,… Continue reading A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent in vitro, ex vivo and in vivo Antiviral Activity
Leah Pandiscia, PhD
July 28, 2017
Two pairs of Zn-based chiral coordination polymers (CCPs), namely, [Zn((R)-cbca)·H2O], [Zn((S)-cbca)]·H2O], [Zn((R)-cna)·2H2O] and [Zn((S)-cna)·2H2O] {H2cbca = (R) or (S)-4′-(1-carboxyethoxy)-[1,1′-biphenyl]-4-carboxylic acid,… Continue reading Two pairs of Zn(II) coordination polymer enantiomers based on chiral aromatic polycarboxylate ligands: synthesis, crystal structures and properties
Leah Pandiscia, PhD
July 28, 2017
The interaction of DNA with Bis [N,N-bis (carboxymethyl) aminomethyl] fluorescein-Ferrous(III) (Fluorescein-DA-Fe(III)) with dual functional (sonodynamic and sonocatalytic) activity was studied… Continue reading Ultrasonic irradiation enhanced the ability of Fluorescein-DA-Fe(III) on sonodynamic and sonocatalytic damages of DNA molecules
Leah Pandiscia, PhD
July 28, 2017
In this work, we designed highly sensitive and selective luminescent detection method for alkaline phosphatase using bovine serum albumin functionalized… Continue reading Sensitive detection of alkaline phosphatase by switching on gold nanoclusters fluorescence quenched by pyridoxal phosphate
Leah Pandiscia, PhD
July 28, 2017
Interaction of quantum dots (QDs) and proteins strongly influenced by the surface characteristics of the QDs at the protein-QD interface.… Continue reading Interaction of insulin with colloidal ZnS quantum dots functionalized by various surface capping agents
Leah Pandiscia, PhD
July 28, 2017
The cytosolic delivery of therapeutic proteins (e.g., antibodies or enzymes) by cell-penetrating peptides (CPPs), such as a human immunodeficiency virus-derived… Continue reading Human-derived fusogenic peptides for the intracellular delivery of proteins
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
ScFv-h3D6 is a single chain variable fragment that precludes Aβ peptide-induced cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway… Continue reading Understanding the contribution of disulphide bridges to the folding and misfolding of an anti-Aβ scFv
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Rassf1A/5 tumor suppressors serve as adaptor proteins possessing a modular architecture with the C-terminal consisting of a coiled-coil SARAH (Salvador-Rassf-Hippo)… Continue reading Rassf Proteins as Modulators of Mst1 Kinase Activity
Leah Pandiscia, PhD
July 28, 2017
Improving power generation under low light condition and capturing electrons efficiently from the photosynthetic bacteria on the electrode are critical… Continue reading FRET guided surging of cyanobacterial photosystems improves and stabilizes current in photosynthetic microbial fuel cell
Leah Pandiscia, PhD
July 28, 2017
Osseointegration between the surface of a certain material and the host tissue helps to evaluate the potential use of biomaterials… Continue reading Biomimetic collagen/phospholipid coatings improve formation of hydroxyapatite nanoparticles on titanium
Leah Pandiscia, PhD
July 28, 2017
Esterases catalyze the cleavage and formation of ester bonds and are members of the diverse family of α/β hydrolase fold.… Continue reading From a metagenomic source to a high-resolution structure of a novel alkaline esterase
Leah Pandiscia, PhD
July 28, 2017