Leah Pandiscia, PhD
July 28, 2017
The study of gold nanoclusters (AuNCs) has seen much interest in recent history due to their unique fluorescent properties and… Continue reading Lysozyme Encapsulated Gold Nanoclusters: Effects of Cluster Synthesis on Natural Protein Characteristics
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Peanuts, whose major allergen is Ara h 2, are included among the eight major food allergens. After reduction using dithiothreitol… Continue reading Ara h 2 cross-linking catalyzed by MTGase decreases its allergenicity
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
G-quadruplex sequences exist in eukaryotic organisms and prokaryotes, and the investigation of interactions between Gquadruplexes and small molecule ligands is… Continue reading Investigation of the interactions between methylene blue and intramolecular G-quadruplexes: an explicit distinction in electrochemical behavior
Leah Pandiscia, PhD
July 28, 2017
A visible light-active, hematite-based photoelectrode platform for suppressing β-amyloid (Aβ) self-assembly in vitro is reported. Upon illumination of a light-emitting… Continue reading Hematite-Based Photoelectrode Materials for Photoelectrocatalytic Inhibition of Alzheimer’s β-Amyloid Self-Assembly
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A supersoluble 40-residue type I antifreeze protein (AFP) was discovered in a righteye flounder, the barfin plaice (bp). Unlike all… Continue reading Concentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Regucalcin is a calcium regulating multifunctional protein reported to have many important functions like calcium homeostasis, anti-oxidative, anti-apoptotic and anti-cancerous… Continue reading Calcium Binding Ability of Recombinant Buffalo Regucalcin: A Study Using Circular Dichroism Spectroscopy
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
α-Synuclein (α-syn), which causally links to Parkinson’s disease, binds to vesicles containing phosphatidic acid (PA). However, the effects of the… Continue reading Dioleoyl-phosphatidic acid selectively binds to α-synuclein and strongly induces its aggregation
Leah Pandiscia, PhD
July 28, 2017
Two new C11-terpenes with an octahydrobenzofuran skeleton, designated ficusnotadiol (1) and ficusnotanone (2), have been isolated from the plant Ficus nota.… Continue reading Two new C11-terpenes with an octahydrobenzofuran skeleton isolated from the leaves of Ficus nota
Leah Pandiscia, PhD
July 28, 2017
Six neolignan glucosides, named isodonosides I–VI, and a megastigmane glucoside named isodonmegastigmane I, were isolated together with 15 known compounds… Continue reading Neolignan and megastigmane glucosides from the aerial parts of Isodon japonicus with cell protective effects on BaP-induced cytotoxicity
Leah Pandiscia, PhD
July 28, 2017
A new lectin was isolated from the marine sponge Aplysina lactuca (ALL) by combining ammonium sulfate precipitation and affinity chromatography on guar… Continue reading Isolation, biochemical characterization and antibiofilm effect of a lectin from the marine sponge Aplysina lactuca
Leah Pandiscia, PhD
July 28, 2017
The versatility of Hsp90 can be attributed to the variety of co-chaperone proteins that modulate the role of Hsp90 in… Continue reading The crystal structure of the Hsp90 co-chaperone Cpr7 from Saccharomyces cerevisiae
Leah Pandiscia, PhD
July 28, 2017
Enzymatic protein hydrolysis is sensitive to modifications of protein structure, e.g. Maillard reaction. In early stages of the reaction glycation… Continue reading Effect of Maillard induced glycation on protein hydrolysis by lysine/arginine and non-lysine/arginine specific proteases
Leah Pandiscia, PhD
July 28, 2017
Four new hygrophorones (1–4) together with the known hygrophorone B12 (5) have been isolated from fruiting bodies of the basidiomycete Hygrophorus abieticola Krieglst.… Continue reading Structural and stereochemical elucidation of new hygrophorones from Hygrophorus abieticola (basidiomycetes)
Leah Pandiscia, PhD
July 28, 2017
Infliximab is therapeutic monoclonal antibody (mAb) against TNF-α employed in the treatment of immunoinflammatory diseases. The development of biosimilar mAbs… Continue reading Extensive preclinical evaluation of an infliximab biosimilar candidate
Leah Pandiscia, PhD
July 28, 2017