Amyloidosis is a group of diseases caused by the accumulation of insoluble protein aggregates in different parts of the body.… Continue reading Lumbrokinase for degradation and reduction of amyloid fibrils associated with amyloidosis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
C-reactive protein (CRP) concentrations rise in response to tissue injury or infection. Circulating pentameric CRP (pCRP) localizes to damaged tissue… Continue reading Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The term “oxidative stress” indicates a set of chemical reactions unleashed by a disparate number of events inducing DNA damage,… Continue reading Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity
Leah Pandiscia, PhD
July 28, 2017
The present study explores preparation and characterization of redox sensitive albumin autogenic nanoparticles (ANPs) for drug delivery applications. Human serum… Continue reading Redox responsive albumin autogenic nanoparticles for the delivery of cancer drugs
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Glucoamylase (EC 3.2.1.3) from Aspergillus niger possesses 31% α-helix, 36% β structure and rest aperiodic structure. A transition of glucoamylase in presence… Continue reading Secondary structural alterations in glucoamylase as an influence of protein aggregation
Leah Pandiscia, PhD
July 28, 2017
Formation of amyloid fibrils has been associated with at least 30 different protein aggregation diseases. The 129-residue polypeptide hen lysozyme,… Continue reading Investigating the effects of erythrosine B on amyloid fibril formation derived from lysozyme
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A novel Schiff base ligand, 2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanone (LH), has been synthesized out of the 1:1 condensation of benzil and 2-hydrazino benzothiazol… Continue reading Synthesis, characterization, structure, DNA binding aspects and molecular docking study of a novel Schiff base ligand and its bis(μ-chloro) bridged Cu(II) dimer
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The development of mitochondria-targeting cell permeable vectors represents a promising therapeutic approach for several diseases, such as cancer and oxidative… Continue reading Development of poly(lactide-co-glycolide) nanoparticles functionalized with a mitochondria penetrating peptide
Leah Pandiscia, PhD
July 28, 2017
Thermophilic Hydrogenophilus thermoluteolus cytochrome c’ (PHCP) exhibits higher thermal stability than a mesophilic counterpart, Allochromatium vinosum cytochrome c’ (AVCP), which has a homo-dimeric structure and ligand-binding… Continue reading Structural and functional insights into thermally stable cytochrome c’ from a thermophile
Leah Pandiscia, PhD
July 28, 2017
PREP1 and PBX1 are homeodomain (HD) transcription factors that play crucial roles in embryonic development. Here, we present the first… Continue reading New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA
Leah Pandiscia, PhD
July 28, 2017
Marine luciferases are regularly employed as useful reporter molecules across a range of various applications. However, attempts to transition expression… Continue reading Expression of a soluble truncated Vargula luciferase in Escherichia coli
Leah Pandiscia, PhD
July 28, 2017
Novel optically active and racemic poly(N-propargylamides) bearing tyrosine pendants (LPT, DPT, and RPT) were synthesized and characterized. The polymers possessed… Continue reading Optically active tyrosine-containing poly(N-propargylamides): Synthesis, helical conformation, and infrared emissivity study
Leah Pandiscia, PhD
July 28, 2017
Applications of graphene have extended into areas of nanobio-technology such as nanobio-medicine, nanobio-sensing, as well as nanoelectronics with biomolecules. These… Continue reading Molecular Interactions between Graphene and Biological Molecules
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017