Leah Pandiscia, PhD
July 28, 2017
Peptidoglycan (PG) is the key component of the bacterial cell wall. The enzyme UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) catalyzes the transfer… Continue reading UDP-N-Acetylglucosamine enolpyruvyl transferase (MurA) of Acinetobacter baumannii (AbMurA): Structural and functional properties
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
This study explores the structural and functional changes associated with a low temperature thermal transition of two engineered bacterial uricase… Continue reading Impact of Mutations on the Higher Order Structure and Activity of a Recombinant Uricase
Leah Pandiscia, PhD
July 28, 2017
γ-PGA-NHS ester, which was prepared using poly(γ-glutamic acid) (γ-PGA) and N-hydroxysuccinimide (NHS) as the raw materials, was synthesized to be… Continue reading The preparation of poly(γ-glutamic acid)-NHS ester as a natural cross-linking agent of collagen
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Glucose-responsive system is one of important options for self-regulated insulin delivery to treat diabetes, which has become an issue of… Continue reading pH-sensitive peptide hydrogel for glucose-responsive insulin delivery
Leah Pandiscia, PhD
July 28, 2017
The role of hemoglobin (Hb) redox forms in tissue and organ toxicities remain ambiguous despite the well-documented contribution of Hb… Continue reading Determination of extinction coefficients of human hemoglobin in various redox states
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
In mammalian assay systems, calcitonin peptides of non-mammalian species exhibit stronger activity than those of mammals. Recently, comparative analyses of… Continue reading Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals
Leah Pandiscia, PhD
July 28, 2017
The physicochemical characteristics, functional properties and amino acid composition of protein extracts from Mung bean were determined and analyzed for… Continue reading Extraction, physicochemical characteristics and functional properties of Mung bean protein
Leah Pandiscia, PhD
July 28, 2017
The α-helical coiled coil is one of the best-studied protein-protein interaction motifs. As a result, sequence-to-structure relationships are available for… Continue reading N@a and N@d: Oligomer- and Partner-specification by Asparagine in Coiled-coil Interfaces
Leah Pandiscia, PhD
July 28, 2017
IgA1 proteases (IgA1P) from diverse pathogenic bacteria specifically cleave human immunoglobulin A1 (IgA1) at the hinge region, thereby thwarting protective… Continue reading Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro
Leah Pandiscia, PhD
July 28, 2017
The conformational characteristics of protected homooligomeric Boc-[β3(R)Val]n-OMe, n = 1, 2, 3, 4, 6, 9 and 12 have been investigated… Continue reading Conformational properties and aggregation of homooligomeric β3(R)-valine peptides in organic solvents
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
In this study, a novel oral insulin delivery system was prepared by combining two different artificial polypeptides with insulin. Negatively… Continue reading Polypeptide-based polyelectrolyte complexes overcoming the biological barriers of oral insulin delivery
Leah Pandiscia, PhD
July 28, 2017
Garcinia nervosa is an abundant source of bioactive phytochemicals. The present paper deals with the isolation of a novel isoflavone 5,7-dihydroxy-3-(3′-hydroxy-4′,5′-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one… Continue reading Structure elucidation, DNA binding specificity and antiproliferative proficiency of isolated compounds from Garcinia nervosa
Leah Pandiscia, PhD
July 28, 2017