A new kind of polymeric chemosensor containing chiral phenylglycine and 1-phenethylamine moieties in the side chain was synthesized by reversible… Continue reading A Chiral Polymer as Chromo-Fluorescence and CD Response Sensor for Specific Recognition of Fluoride
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Lactic acid bacteria (LAB) are sources of a large variety of microbial ester hydrolases because they can produce a wide… Continue reading Characterization of a novel SGNH-type esterase from Lactobacillus plantarum
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Platensimycin (PTM), produced by several strains of Streptomyces platensis, is a promising drug lead for infectious diseases and diabetes. The recent… Continue reading A facile semi-synthetic approach towards halogen-substituted aminobenzoic acid analogues of platensimycin
Leah Pandiscia, PhD
July 28, 2017
Eight new isopimarane diterpene glucosides (1–8) and one new nor-diterpene glucoside (9) were isolated from the twigs and leaves of Lyonia… Continue reading Isopimarane and nor-diterpene glucosides from the twigs and leaves of Lyonia ovalifolia
Leah Pandiscia, PhD
July 28, 2017
Phytochemical investigation of the ethanol extract of whole plants of Iris japonica led to the isolation of three new and eight known… Continue reading Bioactive flavonoid glycosides from Whole Plants of Iris japonica
Leah Pandiscia, PhD
July 28, 2017
A new anionic biosurfactant protein (SP16) has been designed capable of tuning foaming behaviour by pH or salt. This biosurfactant… Continue reading Design of a new switchable biosurfactant protein: from folding to function
Leah Pandiscia, PhD
July 28, 2017
2′-5′-linked RNAs play important roles in many biological systems. In addition, the mixture of 2′-5′ and 3′-5′ phosphodiester bonds have… Continue reading Structural insights into RNA duplexes with multiple 2′-5′-linkages
Leah Pandiscia, PhD
July 28, 2017
DNA is believed to be a promising candidate for molecular logic computation, and the fluorogenic/colorimetric substrates of G-quadruplex DNAzyme (G4zyme)… Continue reading Tyramine-HCl Based Label-free System for Operating Various DNA Logic Gates and a DNA Calliper for Base Number Measurement
Leah Pandiscia, PhD
July 28, 2017
Cytochrome c is an important electron transfer carrier in mitochondrial electron transfer and is essential for apoptosis. In the present… Continue reading Effect of platinum anticancer drugs on the cytochrome c conformation
Leah Pandiscia, PhD
July 28, 2017
Intervention into amyloid deposition with anti-amyloid agents like the polyphenol Epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy… Continue reading Aggregation of Full Length Immunoglobulin Light Chains from AL Amyloidosis Patients Is Remodeled by Epigallocatechin-3-gallate
Leah Pandiscia, PhD
July 28, 2017
To improve the stability of the collagen, here we studied the interaction of chromium(III) polyphenolic complex, [Cr(GA)2] (GA: Gallic acid)… Continue reading Effect of chromium(III) gallate complex on stabilization of collagen
Leah Pandiscia, PhD
July 28, 2017
An efficient asymmetric Michael reaction of 1,3-dicarbonyl compounds with α-Substituted-β-Nitroacrylates has been developed by using a cinchona-thiourea bifunctional organocatalyst in… Continue reading Organocatalytic enantioselective Michael reaction of 1,3-dicarbonyls with α-substituted β-nitroacrylates
Leah Pandiscia, PhD
July 28, 2017
Seven pairs of sesquiterpenes (1a/1be7a/7b), a new peroxy-bridge sesquiterpene (8), and a new peroxybridge norsesquiterpene (9), together with five known… Continue reading Bioactive sesquiterpenoids from the roots of Artabotrys hexapetalus
Leah Pandiscia, PhD
July 28, 2017
Lytic and cell-penetrating peptides (CPPs) are both membrane-active peptides sharing similar physicochemical properties. Although their respective functions have been intensively… Continue reading How charge distribution influences the function of membrane-active peptides: Lytic or cell-penetrating?
Leah Pandiscia, PhD
July 28, 2017
G-quadruplexes (G4) are one of the several different forms of non-canonical DNA structures that can occur in our genome. Their… Continue reading NMR based model of human telomeric repeat G-quadruplex in complex with 2,4,6-triarylpyridine family ligand
Leah Pandiscia, PhD
July 28, 2017
Xyloglucan is the most abundant hemicellulose in primary walls of spermatophytes except for grasses. Xyloglucan-degrading enzymes are important in lignocellulosic… Continue reading Xyloglucan breakdown by endo-xyloglucanase family 74 from Aspergillus fumigatus
Leah Pandiscia, PhD
July 28, 2017
Haemophilia B is caused by genetic aberrations in the F9 gene. The majority of these are non-synonymous mutations that alter… Continue reading Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B
Leah Pandiscia, PhD
July 28, 2017