Leah Pandiscia, PhD
July 28, 2017
Naturally-bioactive hydrogels like gelatin provide favorable properties for tissue-engineering but lack sufficient mechanical strength for use as implantable tissue engineering… Continue reading Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications
Leah Pandiscia, PhD
July 28, 2017
We investigated the effects of nanoparticles (NPs) on the structure and activity of hen egg-white lysozyme (HEWL) using CeO2 and ZnO… Continue reading Effects of metal oxide nanoparticles on the structure and activity of lysozyme
Leah Pandiscia, PhD
July 28, 2017
The conformation and thermodynamic stability of monomeric GroEL were studied by CD and fluorescence spectroscopy. GroEL denaturation with urea and… Continue reading Folding and Unfolding Pathway of Chaperonin GroEL Monomer and Elucidation of Thermodynamic Parameters
Leah Pandiscia, PhD
July 28, 2017
RNA targeting through small molecules is an emerging and promising therapeutic route that necessitates identification of small molecules that can… Continue reading Binding interaction of phenothiazinium dyes with double stranded RNAs: Spectroscopic and calorimetric investigation
Leah Pandiscia, PhD
July 28, 2017
Se-GFP-22, a heteropolysaccharide, with a weight-average Mw of 4.13 × 106 Da, was purified from the crude Se-polysaccharide (Se-GFP) isolated from fruit bodies of… Continue reading Structural elucidation and antioxidant activity of a novel Se-polysaccharide from Se-enriched Grifola frondosa
Leah Pandiscia, PhD
July 28, 2017
The interaction of a new macrocyclic copper complex, [CuL(NO3)2] in which L is 1,3,6,10,12,15-hexaaza tricyclo[13.3.1.16,10] eicosane was investigated in vitro… Continue reading Experimental and molecular modeling studies on the DNA-binding of diazacyclam-based acrocyclic copper complex
Leah Pandiscia, PhD
July 28, 2017
Many Pseudomonas spp. produce cyclic lipodepsipeptides (CLPs), which, besides their role in biological functions such as motility, biofilm formation and interspecies interactions,… Continue reading Membrane Interactions of Natural Cyclic Lipodepsipeptides of the Viscosin Group
Leah Pandiscia, PhD
July 28, 2017
Evaluation of in vitro cytotoxicity of several Cu chelating agents – 2,2′-biquinoline, 8-hydroxyquinoline (oxine), ammonium pyrrolidinedithiocarbamate (APDTC), di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT), dithizone and neocuproine… Continue reading Comparative in vitro investigation of anticancer copper chelating agents
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Proteolysis within the membrane is catalyzed by a diverse family of proteases immersed within the hydrophobic environment of cellular membranes.… Continue reading Enzymatic Assays for Studying Intramembrane Proteolysis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Immunoglobulin Y (IgY) is a new therapeutic antibody, and its applications in industry are very broad. To provide insight into… Continue reading The impact of N-glycosylation on conformation and stability of immunoglobulin Y from egg yolk
Leah Pandiscia, PhD
July 28, 2017
This paper describes the synthesis of a trinuclear Cu(II) complex (4) containing a central 1,4,5,8,9,12-hexaazatriphenylene-hexacarboxylate (hat) core (3). Low, micromolar… Continue reading An unlikely DNA cleaving agent: A photo-active trinuclear Cu(II) complex based on hexaazatriphenylene
Leah Pandiscia, PhD
July 28, 2017
New molecular complexes of l-leucine and d-leucine with chloranilic acid have been synthesized. Crystal structures of these crystals have been solved; they… Continue reading Spectroscopic, thermal and structural studies of new l-leucine and d-leucine complexes with chloranilic acid
Leah Pandiscia, PhD
July 28, 2017
Hydrosoluble glycogen is the major energy storage compound in bacteria, archaea, fungi, and animal cells. In contrast, photosynthetic eukaryotes have… Continue reading Identification of a novel starch synthase III from the picoalgae Ostreococcus tauri
Leah Pandiscia, PhD
July 28, 2017
Single-handed helical silica nanotubes doped with CdS nanoparticles are prepared through a supramolecular templating approach using a pair of chiral… Continue reading Chiroptical activity of single-handed helical silica nanotubes doped with CdS nanoparticles
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The Ebola and Marburg viruses are some of the deadliest viruses in the world. In this study a series of… Continue reading Ebola virus derived G-quadruplexes: Thiazole Orange Interaction
Leah Pandiscia, PhD
July 28, 2017