Leah Pandiscia, PhD
July 28, 2017
The EGFR/ErbB family of receptor tyrosine kinases includes oncogenes important in the progression of breast and other cancers and they… Continue reading Biophysical Evidence for Intrinsic Disorder in the C-terminal Tails of the EGFR and HER3 Receptor Tyrosine Kinases
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Synthesis, characterization and bovine serum albumin (BSA) binding properties of three derivatives of vitamin K3 have been described. Results of… Continue reading Synthesis, characterization and serum albumin binding studies of vitamin K3 derivatives
Leah Pandiscia, PhD
July 28, 2017
Alginate, a polysaccharide that gels in the presence of divalent ions is an obvious component of an injectable gel for… Continue reading Effect of peptide self-assembly on the rheological properties of alginate-peptide conjugates solutions
Leah Pandiscia, PhD
July 28, 2017
Targeted nano-delivery vehicles were developed from genetically modified Cowpea chlorotic mottle virus (CCMV) capsid by ligands bioconjugation for efficient drug delivery in… Continue reading Targeted delivery system for cancer cells consist of multiple ligands conjugated genetically modified CCMV capsid on doxorubicin GNPs complex
Leah Pandiscia, PhD
July 28, 2017
This paper describes data related to the research article “Testing the dependence of stabilizing effect of osmolytes on the fractional… Continue reading Data on the role of accessible surface area on osmolytes-induced protein stabilization
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Here we have reported a detail study on the interaction of the benzophenanthridine alkaloid chelerythrine (CHL) with double stranded polyriboadenylic… Continue reading Spectroscopic study on the binding of chelerythrine with duplex poly (rA): A model of RNA intercalation
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The proline residue in a protein sequence generates constrains to its secondary structure as the associated torsion angles become a… Continue reading Envisaging Structural Insight of a Terminally Protected Proline Dipeptide by Raman Spectroscopy and DFT Analyses
Leah Pandiscia, PhD
July 28, 2017
Interleukin-11 (IL-11) has been expected as a drug on severe thrombocytopenia caused by myelo-suppressive chemotherapy. Whereas, development of IL-11 inhibitor… Continue reading Production and characterization of genetically modified human IL-11 variants
Leah Pandiscia, PhD
July 28, 2017
Human serum amyloid A (SAA) is a precursor protein of AA amyloidosis and a component of high-density lipoproteins (HDLs), thus… Continue reading Effect of lipid environment on amyloid fibril formation of human serum amyloid A
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The first dinuclear metal-mediated base pair containing divalent metal ions has been prepared. A combination of the neutral bis(monodentate) purine… Continue reading A Dinuclear Mercury(II)-Mediated Base Pair in DNA
Leah Pandiscia, PhD
July 28, 2017
A MYC sequence forming an intramolecular G-quadruplex with a parallel topology was modified by the incorporation of 8-bromoguanosine (BrG) analogs in one… Continue reading Observation of a Dynamic G-Tetrad Flip in Intramolecular G-Quadruplexes
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
(R)-1,1’-Bi(2-naphthol) ((R)-BINOL) in an acetonitrile solution lost optical activity upon irradiation with an Hg–Xe lamp. HPLC resolution of the product… Continue reading Photo Racemization and Polymerization of (R)-1,1′-Bi(2-naphthol)
Leah Pandiscia, PhD
July 28, 2017
Slingshot-1 (SSH1) is a protein phosphatase that specifically dephosphorylates and activates cofilin, an F-actin-severing protein. SSH1 binds to and co-localizes… Continue reading A pleckstrin homology-like domain is critical for F-actin binding and cofilin-phosphatase activity of Slingshot-1
Leah Pandiscia, PhD
July 28, 2017
Following the cloning and expression of tobacco (Nicotiana tabacum) phytaspase gene in Escherichia coli BL21, the recombinant protease was purified by affinity… Continue reading Heterologous Expression and Functional Characterization of Phytaspase, a Caspase-Like Plant Protease
Leah Pandiscia, PhD
July 28, 2017