Six eremophilane-type (parasenolide A–F) and an eudesmane-type (parasenin) sesquiterpenoids, along with eight known sesquiterpenes, were isolated from the whole plants… Continue reading Sesquiterpenes from the whole plants of Parasenecio roborowskii
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
SerpinI2/Pancpin/MEPI is a 46 kDa member of the serpin (serine protease inhibitor) superfamily. It is downregulated in pancreatic and breast cancer,… Continue reading SerpinI2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin
Leah Pandiscia, PhD
July 28, 2017
The characterization of conformational and oligomeric distribution of proteins is of paramount importance for the understanding of the correlation between… Continue reading Polymorphic distribution of proteins in solution by mass spectrometry: The analysis of insulin analogues
Leah Pandiscia, PhD
July 28, 2017
This study uses EPR, CD, and fluorescence spectroscopy to examine the structure of bradykinin (BK) analogues attaching the paramagnetic amino… Continue reading Paramagnetic bradykinin analogues as substrates for angiotensin I-converting enzyme: pharmacological and conformation studies
Leah Pandiscia, PhD
July 28, 2017
Three new Amaryllidaceae alkaloids, named zephycandidines I−III (1–3), were isolated from Zephyranthes candida. The structures of 1−3 were elucidated by spectroscopic analyses including… Continue reading Amaryllidaceae alkaloids with new framework types from Zephyranthes candida as potent acetylcholinesterase inhibitors
Leah Pandiscia, PhD
July 28, 2017
In this work, some important characteristics of surface layer (S-layer) proteins extracted from two new and native Lactobacillus strains, L.brevis KM3 and L.brevis KM7,… Continue reading Characteristics of surface layer proteins from two new and native strains of Lactobacillus brevis
Leah Pandiscia, PhD
July 28, 2017
Four new picrotoxane terpenoids, austrobuxusin A–D (1–4), were isolated from the Australian endemic plant Austrobuxus swanii. Their structures were fully characterized… Continue reading New picrotoxane terpenoids, austrobuxusin A-D, from the Australian endemic plant Austrobuxus swanii
Leah Pandiscia, PhD
July 28, 2017
The aims of this study were to predict, identify and characterize pine nut allergens. Korean pine (Pinus koraiensis) vicilin was… Continue reading Identification, characterization, and initial epitope mapping of a pine nut allergen
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Despite of the importance of enantiomers, the fluorescence sensing of enantiomers and the interpretation of the “preferential interaction” still remain… Continue reading Sensing Tyrosine Enantiomers by Using Chiral CdSe/CdS Quantum Dots Capped with N-Acetyl-L-Cysteine
Leah Pandiscia, PhD
July 28, 2017
The quenching interaction of atomoxetine (ATX) with bovine serum albumin (BSA) was studied in vitro under optimal physiological condition (pH=7.4)… Continue reading Multi-spectroscopic characterization of bovine serum albumin upon interaction with atomoxetine
Leah Pandiscia, PhD
July 28, 2017
Endolysins constitute a promising class of antibacterials against Gram-positive bacteria. Recently, endolysins have been engineered with selected peptides to obtain… Continue reading ‘Artilysation’ of endolysin λSa2lys strongly improves its enzymatic and antibacterial activity against streptococci
Leah Pandiscia, PhD
July 28, 2017
One new griseofulvin derivative, (+)-5-chlorogriseofulvin (1), together with two known analogues, griseofulvin (2) and dechlorogriseofulvin (3), was isolated from the… Continue reading A New Griseofulvin Derivative from the Marine-Derived Arthrinium sp. Fungus and Its Biological Activity
Leah Pandiscia, PhD
July 28, 2017
In the photosynthetic apparatus of plants and algae, the major Light-Harvesting Complexes (LHCII) collect excitations and funnel these to the… Continue reading Disentangling protein and lipid interactions that control a molecular switch in photosynthetic light harvesting
Leah Pandiscia, PhD
July 28, 2017
Hexanucleotide repeat expansions in C9orf72 are the most common inherited cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The expansions… Continue reading Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Bovine pancreatic ribonuclease A (RNase A) is the monomeric prototype of the so-called secretory ‘pancreatic-type’ RNase super-family. Like the naturally… Continue reading Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The AT-rich genome of P. falciparum has uniquely localized G-rich stretches that have propensity to form G-quadruplexes. However, their global occurrence and… Continue reading Genome-wide regulatory dynamics of G-quadruplexes in human malaria parasite Plasmodium falciparum
Leah Pandiscia, PhD
July 28, 2017