Recently reported new phenomenon of Aggregation-Induced Raman Optical Activity is demonstrated here for the first time in the pre-resonance conditions… Continue reading Pre-resonance enhancement of exceptional intensity in aggregation-induced Raman optical activity spectra of lutein derivatives
Leah Pandiscia, PhD
July 28, 2017
Enzymes isolated from extremophiles often exhibit superior performance and potential industrial applications. There are several advantages performing biocatalysis at elevated… Continue reading Characterization and Low-Resolution Structure of an Extremely Thermostable Esterase of Potential Biotechnological Interest from Pyrococcus furiosus
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A facile strategy was developed to fabricate structure controllable microcrystals of ferrocene-based metal–organic (Fc-Ala-BCB) materials through evaporation-induced self-assembly. Two distinctive… Continue reading Shape-Controlled Synthesis of Organometallic Microcrystal-Based Hollow Hexagonal Micromotors through Evaporation-Induced Supramolecular Self-Assembly
Leah Pandiscia, PhD
July 28, 2017
The protein alpha-synuclein (αS) self-assembles into toxic beta-sheet aggregates in Parkinson’s disease, while it is proposed that αS forms soluble… Continue reading Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein
Leah Pandiscia, PhD
July 28, 2017
Misfolded β-sheet-rich protein aggregates termed amyloid, deposit in vivo leading to debilitating diseases such as Alzheimer’s, prion and renal amyloidosis diseases etc.… Continue reading Wild-type hen egg white lysozyme aggregation in vitro can form self-seeding amyloid conformational variants
Leah Pandiscia, PhD
July 28, 2017
A covalent organic helical cage with D3 symmetry bearing two trimethylphenyl and six diethynylallene moieties was synthesized. This cage favors… Continue reading Covalent Organic Helical Cages as Sandwich Compound Containers
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The cytochrome P450 aromatase is involved in the last step of sex hormones biosynthesis by converting androgens into estrogens. The… Continue reading Impact of R264C and R264H polymorphisms in human aromatase function
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Cholera toxin (CT) moves from the cell surface to the endoplasmic reticulum (ER) by vesicular transport. In the ER, the… Continue reading Conformational Instability of the Cholera Toxin A1 Polypeptide
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
C2-symmetric binaphthol derivatives bearing two bulky C3-symmetric triphenylsilyl side groups, open-style 3,3′-bis(triphenylsilyl)-1,1′-bi-2-naphthol and closed-style 3,3′-bis(triphenylsilyl)-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate, emit circularly polarized luminescence (CPL)… Continue reading Binaphthyl luminophores with triphenylsilyl groups: sign inversion of circularly polarized luminescence and circular dichroism
Leah Pandiscia, PhD
May 24, 2018
Methoprene tolerant protein (Met) has recently been confirmed as the long-sought juvenile hormone (JH) receptor. This protein plays a significant… Continue reading Intrinsic Disorder of the C-Terminal Domain of DrosophilaMethoprene-Tolerant Protein
Leah Pandiscia, PhD
July 28, 2017
The insomniac protein of Drosophila melanogaster (INC) has a crucial role in sleep homeostasis as flies lacking the inc gene exhibit strikingly… Continue reading Proteins involved in sleep homeostasis: biophysical characterization of INC and its partners
Leah Pandiscia, PhD
July 28, 2017