An efficient ultrasonic-cellulase-assisted extraction (UCE) of Cistanche tubulosapolysaccharide (CTP) was established. The response surface methodology based on Box-Behnken Design was employed… Continue reading Extraction, purification, characterization and antioxidant activities of polysaccharides from Cistanche tubulosa
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The G-quadruplex motif has been widely used for the construction of analytical detection platforms due to its rich structural polymorphism… Continue reading A G-quadruplex-selective luminescent iridium(III) complex and its application by long lifetime
Leah Pandiscia, PhD
July 28, 2017
Novel hybrid materials of cellulose and magnetic nanoparticles (NPs) were synthesized and characterized. The materials combine the chiral nematic structural… Continue reading Magnetic Mesoporous Photonic Cellulose Films
Leah Pandiscia, PhD
July 28, 2017
Glutathione-coordinated [2Fe-2S] complex is a non-protein-bound [2Fe-2S] cluster that is capable of reconstituting the human iron-sulfur cluster scaffold protein IscU.… Continue reading Glutathione-complexed [2Fe-2S] clusters function in Fe–S cluster storage and trafficking
Leah Pandiscia, PhD
July 28, 2017
Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part ofClerodendranthus spicatus. Their structures were elucidated… Continue reading Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus
Leah Pandiscia, PhD
July 28, 2017
We report a simple and facile strategy for the preparation of multifunctional nanoparticles with programmable properties using self-assembly of precisely… Continue reading One-Dimensional Supramolecular Nanoplatforms for Theranostics Based on Co-Assembly of Peptide Amphiphiles
Leah Pandiscia, PhD
July 28, 2017
Structural characterization of amyloid rich in cross-β structures is crucial for unraveling the molecular basis of protein misfolding and amyloid… Continue reading Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid
Leah Pandiscia, PhD
July 28, 2017
The effect of different degree of hydrolysis (DH) by Alcalase on the structural and interfacial properties of sunflower protein isolates… Continue reading Effect of Hydrolysis Degree on Structural and Interfacial Properties of Sunflower Protein Isolates
Leah Pandiscia, PhD
July 28, 2017
Methylglyoxal synthase (MGS) is a homohexameric enzyme responsible for converting dihydroxyacetone phosphate (DHAP) to methylglyoxal and phosphate in the methylglyoxal… Continue reading An alternative allosteric pathway in thermophilic methylglyoxal synthase
Leah Pandiscia, PhD
July 28, 2017
Pressure can influence the folding of nucleic acids, and the effect of pressure depends on the volumetric difference between folded… Continue reading Pressure Effect on the Folding of G-Quadruplex DNA Modified with Hexaethylene Glycol
Leah Pandiscia, PhD
July 28, 2017
Two pairs of unusual scalemic enantiomers with a novel carbon skeleton of 2-[1′-(4″-hydroxy-3″,5″-dimethoxyphenyl)ethyl]-2-methoxyindolin-3-one, named isatidifoliumindolinones A–D (1–4), were isolated from… Continue reading Two pairs of unusual scalemic enantiomers from Isatis indigotica leaves
Leah Pandiscia, PhD
July 28, 2017
Postsynaptic densities (PSDs) are membrane semi-enclosed, submicron protein-enriched cellular compartments beneath postsynaptic membranes, which constantly exchange their components with bulk… Continue reading Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
Leah Pandiscia, PhD
July 28, 2017
Calcium (Ca2+) flux into the matrix is tightly controlled by the mitochondrial Ca2+ uniporter (MCU) due to vital roles in cell… Continue reading Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations
Leah Pandiscia, PhD
July 28, 2017
Four new lignans, alashinols A–D (1–4), a new hydrolysis product, alashinols E (5), and seven known analogues were isolated from… Continue reading Lignans from the stem bark of Syringa pinnatifolia
Leah Pandiscia, PhD
July 28, 2017
The understanding and controlling of biomimetic hybrid materials are a key objective in bio-nanotechnology, materials chemistry, and colloid science fields.… Continue reading Protein-Directed Assembly of Cobalt Phosphate Hybrid Nanoflowers
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Microbial resistance to conventional antibiotics is a public health problem worldwide, motivating the search for new therapeutic alternatives in varied… Continue reading Stigmurin and TsAP-2 from Tityus stigmurus scorpion venom: Assessment of structure and therapeutic potential in experimental sepsis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
May 24, 2018
Seven new cadinane-type sesquiterpenoids (1–7) were isolated from the rhizomes ofStahlianthus involucratus. The planar structures of 1–7 were elucidated on the basis… Continue reading Cadinane-type sesquiterpenoids from Stahlianthus involucratus and their absolute configurations
Leah Pandiscia, PhD
July 28, 2017