Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The structural effect induced by therapeutic ultrasound on proteins in aqueous solution has been investigated with FTIR spectroscopy, UV–VIS spectroscopy,… Continue reading Structural changes induced in proteins by therapeutic ultrasounds
Leah Pandiscia, PhD
July 28, 2017
Two new flavanoids, 5,7-dimethoxy-3′,4′-methylenedioxyflavanone and isobonducellin along with 2′-hydroxy-2,3,4′,6′-tetramethoxychalcone, 5,7-dimethoxyflavone and bonducellin were isolated from the aerial parts of Caesalpinia pulcherrima.… Continue reading Flavanoids from Caesalpinia pulcherrima
Leah Pandiscia, PhD
July 28, 2017
In this review article we examine state-of-the-art techniques for the structural elucidation of organic compounds isolated from natural sources. In… Continue reading Absolute structural elucidation of natural products—A focus on quantum-mechanical calculations of solid-state CD spectra
Leah Pandiscia, PhD
July 28, 2017
Protein films represent an interesting class of materials with various possibilities for applications. We investigated films made of two different… Continue reading Processing and modification of films made from recombinant spider silk proteins
Leah Pandiscia, PhD
July 28, 2017
In this study, a flexible amine-functionalized triphenylamine dye 2 was developed and utilized as a G4 DNA fluorescent probe. The selectivity, sensitivity… Continue reading Flexible amine-functionalized triphenylamine derivative as a fluorescent “light-up” probe for G-quadruplex DNA
Leah Pandiscia, PhD
July 28, 2017
Mangosteen (Garcinia mangostana, Clusiaceae) is called “queen of fruit” in Southeast Asia. In the current study, three dimeric xanthones, garcinoxanthones… Continue reading Nitric oxide inhibitory xanthones from the pericarps of Garcinia mangostana
Leah Pandiscia, PhD
July 28, 2017
DNA polymerase processivity factors are ubiquitously present in all living organisms. Notwithstanding their high significance, the molecular details of clamps… Continue reading On the domains of T4 phage sliding clamp gp45: An intermolecular crosstalk governs structural stability and biological activity
Leah Pandiscia, PhD
July 28, 2017
This work successfully investigated the effects of different influential factors and hydrophobic cavities of cyclodextrins (CDs) on α-galactosidase (α-Gal) by… Continue reading Inhibition of Cyclodextrins on α-Galactosidase
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The goal of this work has been to synthesize and investigate Pd(TC3), an intercalating porphyrin that has conformable substituents capable… Continue reading DNA binding of Pd(TC3), a conformable cationic porphyrin with a long-lived triplet state
Leah Pandiscia, PhD
July 28, 2017
Arginine is one of the universal reagents that are effective in assisting refolding of recombinant proteins from inclusion bodies. The… Continue reading The effects of arginine on refolding of aggregated proteins: not facilitate refolding, but suppress aggregation ☆
Leah Pandiscia, PhD
July 28, 2017
The cathelin-like domain (CLD) of the antimicrobial cathelicidin family constitutes a unique protein family with structural similarity to cystatins, the… Continue reading Activation of cathepsin L by the cathelin-like domain of protegrin-3
Leah Pandiscia, PhD
July 28, 2017
Human plasma protein binding of six antimalarial agents of quinoline and acridine types was investigated by using spectroscopic techniques, affinity… Continue reading Selective plasma protein binding of antimalarial drugs to α1-acid glycoprotein
Leah Pandiscia, PhD
July 28, 2017
This manuscript describes a protocol for the fast determination of identity, enantiomeric excess (ee) and concentration of chiral 1,2-diamines, the… Continue reading High-Throughput Screening of Identity, Enantiomeric Excess, and Concentration Using MLCT Transitions in CD Spectroscopy
Leah Pandiscia, PhD
July 28, 2017
The tau protein plays an important role in some neurodegenerative diseases including Alzheimer’s disease (AD). Neurofibrillary tangles (NFTs), a biological… Continue reading Binding of copper (II) ion to an Alzheimer’s tau peptide as revealed by MALDI-TOF MS, CD, and NMR
Leah Pandiscia, PhD
July 28, 2017
The synthesis and folding behavior of two different series of double hydrophilic block copolymers based on polyethyleneglycol and short acidic… Continue reading Double hydrophilic block copolymers with switchable secondary structure as additives for crystallization control
Leah Pandiscia, PhD
July 28, 2017
Strongly white-emitting (λmax = 495 ± 10 nm) D- and L- penicillamine capped CdS nanoparticles, which show strong circular dichroism in the range 200–390 nm,… Continue reading Chiral highly luminescent CdS quantum dots
Leah Pandiscia, PhD
July 28, 2017