Leah Pandiscia, PhD
July 28, 2017
We isolated 16 new xestoquinone derivatives, including two trimers, six dimers, and four monomers with containing thiomorpholine 1,1-dioxide and pyrrolidine-2,4-diol… Continue reading Petroquinones: trimeric and dimeric xestoquinone derivatives isolated from the marine sponge Petrosia alfiani
Leah Pandiscia, PhD
July 28, 2017
Antimicrobial peptides have long been considered as promising compounds against drug-resistant pathogens. In this work, we studied the secondary structure… Continue reading Conformational study of melectin and antapin antimicrobial peptides in model membrane environments
Leah Pandiscia, PhD
July 28, 2017
The thermodynamic study of the binding of sulphanilic acid with model transport protein bovine serum albumin is a promising approach… Continue reading Physicochemical aspects of the energetics of binding of sulphanilic acid with bovine serum albumin
Leah Pandiscia, PhD
July 28, 2017
Two new homoisoflavonoids, dracaeconolide A (1) and dracaeconolide B (2), together with ten known compounds, namely (3R)-7,4′-dihydroxy-8-methoxyhomoisoflavane (3), (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane (4),… Continue reading Isolation and chatacterization of homoisoflavonoids from Dracaena cochinchinensis and their osteogenic activities in mouse mesenchymal stem cells
Leah Pandiscia, PhD
July 28, 2017
We describe the synthesis, 3D-derived quantitative structure-activity relationship (QSAR), antiproliferative activity and DNA binding properties of a series of 2-amino,… Continue reading Amino substituted benzimidazo[1,2-a]quinolines: Antiproliferative potency, 3D QSAR study and DNA binding properties
Leah Pandiscia, PhD
July 28, 2017
Copper(II) complex formation processes between the alloferon 1 (Allo1) (HGVSGHGQHGVHG) analogues where the tryptophan residue is introducing in the place… Continue reading High stability and biological activity of the copper(II) complexes of alloferon 1 analogues containing tryptophan
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Human Hsp70-2 is a chaperone expressed mainly in the nervous system. Up to now, no study has reported on the… Continue reading Recombinant human Tat-Hsp70-2: A tool for neuroprotection
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Interaction of the food colorant tartrazine with human hemoglobin was studied using multispectroscopic and microcalorimetric techniques to gain insights into… Continue reading Multispectroscopic and calorimetric studies on the binding of the food colorant tartrazine with human hemoglobin
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The π-conjugated tetrathiafulvalene (TTF) annulated ligand was introduced into a dicyanometallate for the first time, leading to the synthesis of… Continue reading Chiral heterobimetallic chains from a dicyanideferrite building block including a π-conjugated TTF annulated ligand
Leah Pandiscia, PhD
July 28, 2017
Biomineralization of the extracellular matrix (ECM) plays a crucial role in bone formation. Functional and structural biomimetic native bone ECM… Continue reading A glycosaminoglycan mimetic peptide nanofiber gel as an osteoinductive scaffold
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
A new sesquilignan, euonymolin A (1), and six known lignans, (-)-de-O-methylmagnolin (2), (+)-de-O-methylepimagnolin A (3), (+)-syringaresinol (4), (+)-pinoresinol (5), (+)-medioresinol… Continue reading Lignans from the Twigs of Euonymus alatus (Thunb.) Sieb. and their Biological Evaluation
Leah Pandiscia, PhD
July 28, 2017
The freezing step in lyophilization is the most determinant for the quality of biopharmaceutics. Using insulin as model of therapeutic… Continue reading Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization
Leah Pandiscia, PhD
July 28, 2017
HIV is primarily transmitted by sexual intercourse and predominantly infects people in Third World countries. Here an important medical need… Continue reading Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide
Leah Pandiscia, PhD
July 28, 2017
Among all proteins localized in the Golgi apparatus, a two-PDZ (PSD95/DlgA/Zo-1) domain protein plays an important role in the assembly… Continue reading New structural insights into Golgi Reassembly and Stacking Protein (GRASP) in solution
Leah Pandiscia, PhD
July 28, 2017