Trimeric autotransporter adhesins (TAAs), cell surface proteins of Gram-negative bacteria, mediate bacterial adhesion to host cells and extracellular matrix proteins.… Continue reading An Acinetobacter trimeric autotransporter adhesin reaped from cells exhibits its nonspecific stickiness via a highly stable 3D structure
Leah Pandiscia, PhD
July 28, 2017
Polyflavanostilbene B (1), an unusual adduct of epicatechin-3-O-gallate fused to piceid through a carbon–carbon bond, four new dimeric stilbene glycosides… Continue reading A novel adduct of ECG fused to piceid and four new dimeric stilbene glycosides from Polygonum cuspidatum
Leah Pandiscia, PhD
July 28, 2017
Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel… Continue reading Angiogenic Peptide Nanofibers Improve Wound Healing in STZ-Induced Diabetic Rats
Leah Pandiscia, PhD
July 28, 2017
Cobalt(III) complexes (1–3) such as [Co(acac)(bpy)(N3)2·H2O] 1, [Co(acac)(en)(N3)2] 2, and [Co(acac)(2-pic)(N3)2] 3 (where, acac = acetylacetone, bpy = 2.2′-bipyridine, en = ethylenediamine, 2-pic = 2-picolylamine and NaN3 = sodium azide) were synthesized and characterized.… Continue reading Cobalt(III) complexes as potential anticancer agents: Physicochemical, structural, cytotoxic activity and DNA/protein interactions
Leah Pandiscia, PhD
July 28, 2017
Bioengineered spider silks are a biomaterial with great potential for applications in biomedicine. They are biocompatible,biodegradable and can self-assemble into… Continue reading The method of purifying bioengineered spider silk determines the silk sphere properties
Leah Pandiscia, PhD
July 28, 2017
Ara h 2 was purified from peanuts that were thermally treated by various processes, including boiling, glycation, frying and roasting.… Continue reading Thermal processing effects on peanut allergen Ara h 2 allergenicity in mice and its antigenic epitope structure
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
High-pressure carbon dioxide (HPCD) is widely used in the food industry, but some scientific issue is still unclear, especially the… Continue reading The Effect of High-Pressure Carbon Dioxide on the Skeletal Muscle Myoglobin
Leah Pandiscia, PhD
July 28, 2017
To identify the structural and functional roles of Glu9 located at the first loop of sweet-tasting brazzein, two different mutants (E9K… Continue reading The effect of charge alteration and flexibility on the function and structural stability of sweet-tasting brazzein
Leah Pandiscia, PhD
July 28, 2017
Conventional conjugated systems are characteristic of only either inherent or induced chirality because of synthetic challenge in combination of chiral… Continue reading Integration of inherent and induced chirality into subphthalocyanine analogue
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
We report the changes in the hydration dynamics around a model protein hen egg white lysozyme (HEWL) in water–dimethyl sulfoxide… Continue reading Preferential solvation of lysozyme in dimethyl sulfoxide/water binary mixture probed by terahertz spectroscopy
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The presence of Lewy bodies and Lewy neurites is a major pathological hallmark of Parkinson’s disease and is hypothesized to… Continue reading Mechanistic study of the inhibitory activity of Geum urbanumextract against α-Synuclein fibrillation
Leah Pandiscia, PhD
July 28, 2017
The synthesis of nanoparticles of conjugates of caffeic acid-modified chitosan with ruthenium arene complexes is described. The chemical structure and… Continue reading Nanoparticles of chitosan conjugated to organo-ruthenium complexes
Leah Pandiscia, PhD
July 28, 2017
Development of an oral delivery strategy for insulin therapeutics has drawn much attention in recent years. In this study, a… Continue reading A composite hydrogel system containing glucose-responsive nanocarriers for oral delivery of insulin
Leah Pandiscia, PhD
July 28, 2017
Versions of a previously discovered β-hairpin peptide inhibitor of IAPP aggregation that are stabilized in that conformation, or even forced… Continue reading Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
In this study, we proposed a loop transplant strategy to improve the thermostability of Penicillium purpurogenum Li-3 β-glucuronidase expressed in Escherichia coli (abbreviated to… Continue reading Engineering the thermostability of β-glucuronidase from Penicillium purpurogenum Li-3 by loop transplant
Leah Pandiscia, PhD
July 28, 2017