Fungal GH12 enzymes are classified as xyloglucanases when they specifically target xyloglucans, or promiscuous endoglucanases when they exhibit catalytic activity… Continue reading Molecular basis of substrate recognition and specificity revealed in family 12 glycoside hydrolases
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Six 6,8-di-C-methyl-flavonoids, (2R,3R)-6,8-di-C-methyl-5,7,4′-trihydroxyflavanonol 7-O-β-d-gluco-pyranoside (1), (2R,3R)-6,8-di-C-methyl-5,7,4′-trihydroxyflavanonol 7-O-β-d-xylopyranosyl(1 → 6)-β-d-glucopyranoside (2), 6,8-di-C-methylkaempferol 7-O-β-d-glucopyranoside (3), (2R)-farrerol (4a), (2R/2S)-farrerol 7-O-β-d-glucopyranoside (5), and (2R/2S)-farrerol 7-O-β-d-xylopyranosyl(1 → 6)-β-d-glucopyranoside (6),… Continue reading 6,8-Di-C-methyl-flavonoids with neuroprotective activities fromRhododendron fortunei
Leah Pandiscia, PhD
July 28, 2017
Mycoplasma pneumoniae is a human pathogen that glides on host cell surfaces with repeated catch and release of sialylated oligosaccharides. At… Continue reading Structural study of MPN387, an essential protein for gliding motility of a human pathogenic bacterium,Mycoplasma pneumoniae
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Ionizing radiation, free radicals, and reactive oxygen species produce hundreds of different DNA lesions. Clustered lesions are typical for ionizing… Continue reading Nuclear Magnetic Resonance Solution Structure of DNA Featuring Clustered 2′-Deoxyribonolactone and 8-Oxoguanine Lesions
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Nora virus is an enteric virus that causes persistent, non-pathological infection inDrosophila melanogaster. It replicates in the fly gut and is… Continue reading VP3 is crucial for the stability of Nora virus virions
Leah Pandiscia, PhD
July 28, 2017
The chemical study on the seeds of Caesalpinia sappan led to the isolation of five new cassane diterpenoids, phanginins R‒T (1–3) and… Continue reading Cytotoxic and Pro-Apoptotic Effects of Cassane Diterpenoids from the Seeds ofCaesalpinia sappan in Cancer Cells
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The eukaryotic protein Isd11 is a chaperone that binds and stabilizes the central component of the essential metabolic pathway responsible… Continue reading The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS
Leah Pandiscia, PhD
July 28, 2017
Metolachlor is a chiral herbicide consisting of four stereoisomers, which is typically used as a racemic mixture or is enriched… Continue reading Metolachlor Stereoisomers: Enantioseparation, Identification and Chiral Stability
Leah Pandiscia, PhD
July 28, 2017
One new bisbenzylisoquinoline alkaloid, neferine N-oxide (1), along with three known compounds, neferine (2), liensinine (3), and isoliensinine (4), were isolated… Continue reading A new bisbenzylisoquinoline alkaloid from Plumulanelumbinis
Leah Pandiscia, PhD
July 28, 2017
Aggregation-induced photon upconversion (iPUC) based on triplet-triplet annihilation (TTA) process is successfully developed by controlled self-assembly of donor-acceptor pairs in… Continue reading All-or-None Switching of Photon Upconversion in Self-Assembled Organogel Systems
Leah Pandiscia, PhD
July 28, 2017
In our continuing search for bioactive constituents from Korean medicinal sources, an investigation of the Sinomenium acutum Rehder et Wilson rhizome afforded… Continue reading Anti-neuroinflammatory constituents from Sinomenium acutumrhizomes
Leah Pandiscia, PhD
July 28, 2017
Triarylmethane derivatives are extensively investigated as antitumor and antibacterial drug candidates alone and as photoactivatable compounds. In the series of… Continue reading Quantitative parameters of complexes of tris(1-alkylindol-3-yl)methylium salts with serum albumin: Relevance for the design of drug candidates
Leah Pandiscia, PhD
July 28, 2017
A new flavonol, 6-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (3) together with two known compounds, kaempferol (4) and 7-O-methyl aromadendrin (5) were isolated from the… Continue reading A new flavonol from the kino of Eucalyptus citriodora
Leah Pandiscia, PhD
July 28, 2017
A new lignan glycoside, 1-[3,6-(4,4′-dihydroxy-3,3′-dimethoxy-δ-truxinyl)-β-fructofuranosyl]-α-glucopyranoside (1), named coixlachryside A, together with nine known simple phenolic compounds (3–11) were isolated from… Continue reading Coixlachryside A: A new lignan glycoside from the roots ofCoix lachryma-jobi L. var. ma-yuen Stapf.
Leah Pandiscia, PhD
July 28, 2017
Transient receptor potential melastatin-1 channel (TRPM1) is an important mediator of calcium influx into the cell that is expressed in… Continue reading The characterization of a novel S100A1 binding site in the N-terminus of TRPM1
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017