Evaluating protein structures in living cells remains a challenge. Here, we investigate Interleukin-4 receptor alpha (IL-4Rα) into which the non-canonical… Continue reading Insights into Receptor Structure and Dynamics at the Surface of Living Cells
Carlos Morillo
April 4, 2023
In order to reduce infection risk of novel coronavirus (SARS-CoV-2), we developed nano-photocatalysts with nanoscale rutile TiO2 (4–8 nm) and CuxO… Continue reading Inactivation and Spike Protein Denaturation of Novel Coronavirus Variants by CuxO/TiO2 Nano-Photocatalysts
Carlos Morillo
April 4, 2023
Mycobacterium tuberculosis Clp proteases are targeted by several antitubercular compounds, including cyclomarin A (CymA). CymA exerts its toxicity by binding… Continue reading ClpC2 Protects Mycobacteria against a Natural Antibiotic Targeting ClpC1-Dependent Protein Degradation
Carlos Morillo
April 4, 2023
Cell adhesion molecules are crucial for a variety of biological processes, including wound healing, barrier formationand tissue homeostasis. One of them… Continue reading HAV-Peptides Attached to Colloidal Probes Faithfully Detect E-Cadherins Displayed on Living Cells
Carlos Morillo
April 4, 2023
Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Streptococcus pyogenes… Continue reading Mechanism of Antibody-Specific Deglycosylation and Immune Evasion by Streptococcal IgG-Specific Endoglycosidases
Carlos Morillo
April 4, 2023
Self-assembled compartments from nanoscale components are found in all life forms. Their characteristic dimensions are in 50?1000 nm scale, typically assembled… Continue reading Self-Organization of Iron Sulfide Nanoparticles into Complex Multi-Compartment Supraparticles
Carlos Morillo
April 4, 2023
Carlos Morillo
April 4, 2023
Surface chemistry influences not only physicochemical properties but also safety and applications of MXene nanomaterials. Fluorinated Ti3C2Tx MXene, synthesized using… Continue reading Biocompatible and Oxidation-Resistant Ti3C2Tx MXene with Halogen-Free Surface Terminations
Carlos Morillo
April 4, 2023
Carlos Morillo
April 4, 2023
Carlos Morillo
April 4, 2023
HCN4 channels are considered to be a promising target for cardiac pathologies, epilepsy, and multiple sclerosis. However, there are no… Continue reading Optimized Synthesis and Pharmacological Evaluation of HCN Channel Inhibitor EC18
Carlos Morillo
April 4, 2023
Mass transfer is a key parameter in heterogeneous reactions. Micro/nanomachines, a promising technology for environmental applications, significantly enhance the performance… Continue reading Metal Oxide Single-Component Light-Powered Micromotors for Photocatalytic Degradation of Nitroaromatic Pollutants
Carlos Morillo
April 4, 2023
Excessive exposure to ultraviolet (UV) and high-energy visible (HEV) light can cause sunburns, wrinkles, and even skin cancer. Therefore, the… Continue reading G-C3N4 Monolayer/2D Mica Nanohybrids with Highly Effective UV–HEV-Screening Function
Carlos Morillo
April 4, 2023
To efficiently combat viral infectious diseases, it is important to develop broadly applicable countermeasures, and efficient antiviral systems can be… Continue reading Photoactive Conjugated Polymer-Based Strategy to Effectively Inactivate RNA Viruses
Carlos Morillo
April 4, 2023
Increasing the number of environmental stressors could decrease ecosystem functioning in soils. Yet this relationship has not been globally assessed… Continue reading Increasing the Number of Stressors Reduces Soil Ecosystem Services Worldwide
Carlos Morillo
April 4, 2023
Iron-nitrenoid complexes can activate C?H bonds and, thus, potentially directly transform C?H into C?N bonds. Low-coordination complexes are the main… Continue reading Octahedral Iron-Acyl-Nitrenoid Intermediates in Sulphur –Nitrogen Coupling and Hydrogen Atom Transfer Reactions
Carlos Morillo
April 4, 2023
Tyrosine nitration, a post-translational modification (PTM) that takes place under nitrosative stress conditions, occurs through a non-enzymatic peroxynitrite-mediated reaction. Although… Continue reading Probing Tyrosine Nitration with a Small Tb(III)-Metallopeptide
Carlos Morillo
April 4, 2023
In this investigation, pressure microwave irradiation was used to clarify the activity of 1-(2-hydroxyphenyl)-3-(4-methylphenyl)prop-2-en-1-one (3) towards several active methylene derivatives… Continue reading Microwave-Assisted Synthesis, Antioxidant Activity, Docking Simulation, and DFT Analysis of Different Heterocyclic Compounds
Carlos Morillo
April 4, 2023
A “synthetic minimal cell” is considered here as a cell-like artificial vesicle reproduction system in which a chemical and physico-chemical transformation… Continue reading Synthesising a Minimal Cell with Artificial Metabolic Pathways
Carlos Morillo
April 4, 2023
Silver nanoparticles (AgNPs) are presented within mesoporous natural fiber welded (NFW) cellulose and demonstrated as robust catalysts to reduce 4-nitrophenol… Continue reading Mesoporous Natural Fiber Welded Cellulose Containing Silver Nanoparticles as a Recyclable Heterogeneous Catalyst
Carlos Morillo
April 4, 2023