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Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine

2014 / Physical Chemistry Chemical Physics

Spectroscopic studies combined with computational analysis indicate the inherent conformational flexibility of the β-carbolin derivative evodiamine (EVD) featured with diverse… Continue reading Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine

Leah Pandiscia, PhD May 22, 2018

Novel heterocyclic thiosemicarbazones derivatives as colorimetric and “turn on” fluorescent sensors for fluoride anion sensing employing hydrogen bonding

2013 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Two novel heterocyclic thiosemicarbazone derivatives have been synthesized, and characterized, by means of spectroscopic and single crystal X-ray diffraction methods.… Continue reading Novel heterocyclic thiosemicarbazones derivatives as colorimetric and “turn on” fluorescent sensors for fluoride anion sensing employing hydrogen bonding

Leah Pandiscia, PhD May 22, 2018

Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

2014 / Neurobiology of Disease

Dementia with Lewy bodies (DLB), Parkinson’s disease (PD) and multiple system atrophy are characterized by the deposition of disease-associated α-synuclein. In the present… Continue reading Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

Leah Pandiscia, PhD May 22, 2018

Design, Synthesis, Physicochemical Studies, Solvation, and DNA Damage of Quinoline-Appended Chalcone Derivative: Comprehensive Spectroscopic Approach toward Drug Discovery

2014 / Journal of Physical Chemistry B

The present study epitomizes the design, synthesis, photophysics, solvation, and interaction with calf-thymus DNA of a potential antitumor, anticancer quinoline-appended… Continue reading Design, Synthesis, Physicochemical Studies, Solvation, and DNA Damage of Quinoline-Appended Chalcone Derivative: Comprehensive Spectroscopic Approach toward Drug Discovery

Leah Pandiscia, PhD May 22, 2018

Complete oxidation of acetaldehyde over a composite photocatalyst of graphitic carbon nitride and tungsten(VI) oxide under visible-light irradiation

2014 / Applied Catalysis B: Environmental

Graphitic carbon nitride (g-C3N4) was prepared by heating melamine and then its specific surface area was enlarged by hydrothermal treatment… Continue reading Complete oxidation of acetaldehyde over a composite photocatalyst of graphitic carbon nitride and tungsten(VI) oxide under visible-light irradiation

Leah Pandiscia, PhD May 22, 2018