Hydrophilic Residues 526KNDAAD531 in the Flexible C-terminal Region of the Chaperonin GroEL Are Critical for Substrate Protein Folding within the Central Cavity

2008 / The Journal of Biological Chemistry

The final 23 residues in the C-terminal region of Escherichia coli GroEL are invisible in crystallographic analyses due to high flexibility. To… Continue reading Hydrophilic Residues 526KNDAAD531 in the Flexible C-terminal Region of the Chaperonin GroEL Are Critical for Substrate Protein Folding within the Central Cavity

Leah Pandiscia, PhD

Biophysical characterization of highly active recombinantGaussia luciferase expressed in Escherichia coli

2010 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Recently, the smallest bioluminescent protein (MW: 19.9 kDa), Gaussia luciferase (GLuc), has been isolated from the marine copepod Gaussia princeps and has attracted much attention… Continue reading Biophysical characterization of highly active recombinantGaussia luciferase expressed in Escherichia coli

Leah Pandiscia, PhD

Mechanistic insight of photo-induced aggregation of chicken egg white lysozyme: The interplay between hydrophobic interactions and formation of intermolecular disulfide bonds

2011 / Proteins: Structure, Function, and Bioinformatics

Recently, it was reported that ultraviolet (UV) illumination could trigger the unfolding of proteins by disrupting the buried disulfide bonds.… Continue reading Mechanistic insight of photo-induced aggregation of chicken egg white lysozyme: The interplay between hydrophobic interactions and formation of intermolecular disulfide bonds

Leah Pandiscia, PhD

DNA binding, antioxidant, cytotoxicity (MTT, lactate dehydrogenase, NO), and cellular uptake studies of structurally different nickel(II) thiosemicarbazone complexes: synthesis, spectroscopy, electrochemistry, and X-ray crystallography

2013 / Journal of Biological Inorganic Chemistry

Three new nickel(II) thiosemicarbazone complexes have been synthesized and characterized by analytical, spectral, and single-crystal X-ray diffraction studies. In complex 1,… Continue reading DNA binding, antioxidant, cytotoxicity (MTT, lactate dehydrogenase, NO), and cellular uptake studies of structurally different nickel(II) thiosemicarbazone complexes: synthesis, spectroscopy, electrochemistry, and X-ray crystallography

Leah Pandiscia, PhD

Optical and Electron Paramagnetic Resonance Studies of the Excited States of 4-tert-Butyl-4′-Methoxydibenzoylmethane and 4-tert-Butyl-4′-Methoxydibenzoylpropane

2009 / Journal of Physical Chemistry A

The excited states of 4-tert-butyl-4′-methoxydibenzoylmethane (BM-DBM) and 4-tert-butyl-4′-methoxydibenzoylpropane (BM-DBP), the model of the keto form of BM-DBM, have been studied… Continue reading Optical and Electron Paramagnetic Resonance Studies of the Excited States of 4-tert-Butyl-4′-Methoxydibenzoylmethane and 4-tert-Butyl-4′-Methoxydibenzoylpropane

Leah Pandiscia, PhD

Enhancement of Photoluminescence in (Gd,Eu)2O(WO4)2 Phosphors by Lanthanum Doping into the Host Gd2O(WO4)2 Lattice

2012 / Journal of Solid State Science and Technology

Red-emitting (Gd1−x−yLaxEuy)2O(WO4)2 (0 ≤ x ≤ 0.05, 0.30 ≤ y ≤ 0.50) phosphors were synthesized by the conventional solid state reaction method. Single phase gadolinium… Continue reading Enhancement of Photoluminescence in (Gd,Eu)2O(WO4)2 Phosphors by Lanthanum Doping into the Host Gd2O(WO4)2 Lattice

Leah Pandiscia, PhD

Photo-physical properties of 2-(1-ethynylpyrene)-adenosine: influence of hydrogen bonding on excited state properties

2014 / Physical Chemistry Chemical Physics

The photo-physical properties of 2-(1-ethynylpyrene)-adenosine (PyA), a fluorescent probe for RNA dynamics, were examined by solvation studies. The excited-state dynamics… Continue reading Photo-physical properties of 2-(1-ethynylpyrene)-adenosine: influence of hydrogen bonding on excited state properties

Leah Pandiscia, PhD

Enhanced luminescent properties of Ca3−xTbxZrSi2O9+x/2 phosphors by Al3+ doping into the Zr4+ site in the host lattice

2014 / Journal of Luminescence

Green-emitting Ca3−xTbxZr1−yAlySi2O9+(x–y)/2 (0.05≤x≤0.20, 0≤y≤0.07) phosphors were synthesized in a single phase form by the conventional solid-state reaction method and their photoluminescent… Continue reading Enhanced luminescent properties of Ca3−xTbxZrSi2O9+x/2 phosphors by Al3+ doping into the Zr4+ site in the host lattice

Leah Pandiscia, PhD

Deep Red Phosphorescence of Cyclometalated Iridium Complexes by o-Carborane Substitution

2014 / Inorganic Chemistry

Heteroleptic (C∧N)2Ir(acac) (C∧N = 5-MeCBbtp (5a); 4-BuCBbtp (5b); 5-BuCBbtp (5c); 5-(R)CBbtp = 2-(2′-benzothienyl)-5-(2-R-ortho-carboran-1-yl)-pyridinato-C2,N, R = Me and n-Bu; 4-BuCBbtp = 2-(2′-benzothienyl)-4-(2-n-Bu-ortho-carboran-1-yl)-pyridinato-C2,N,… Continue reading Deep Red Phosphorescence of Cyclometalated Iridium Complexes by o-Carborane Substitution

Leah Pandiscia, PhD