2022 / Nano select
Macrocyclic drugs are promising agents for treating a variety of diseases. However, these compounds usually present delivery limitations, such as… Continue reading Mechanically interlocked molecular architectures of valinomycin as cancer targeted prodrugs
2022 / Ecology and Evolution
Trait expression of natural populations often jointly depends on prevailing abiotic environmental conditions and predation risk. Copepods, for example, can… Continue reading The influence of predator community composition on photoprotective traits of copepods
2022 / microbial biotechnology
Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable… Continue reading Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601
2022 / Scientific reports
Osteoarthritis (OA) is a chronic degenerative joint disease associated with age, mechanical stress, and obesity. Echinacea purpurea is a medicinal… Continue reading Protective effect of ethanolic extract of Echinacea purpurea contained nanoparticles on meniscal/ligamentous injury induced osteoarthritis in obese male rats
2022 / Macro Moldecular chemistry and physics
Melanins are a class of biopolymers that are widespread in nature, with diverse origins, compositions, and functions, and their chemical… Continue reading The Polymerization of Homogentisic Acid In Vitro as a Model for Pyomelanin Formation
2022 / Macro Moldecular materials and engineering
Stereolithography is a lithography-based additive manufacturing technology, in which liquid photoreactive resins are solidified by ultraviolet or visible light in… Continue reading Novel Thiol-Ene Photo Resins for Stereolithography with Enhanced Mechanical and Optical Properties
2022 / Cell Discovery
The conserved ATPase p97 (Cdc48 in yeast) and adaptors mediate diverse cellular processes through unfolding polyubiquitinated proteins and extracting them… Continue reading Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state
2022 / npj Biofilms and Microbiomes
Cardiovascular disease (CVD) is strongly associated with the gut microbiota and its metabolites, including trimethylamine-N-oxide (TMAO), formed from metaorganismal metabolism… Continue reading Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation
2022 / Scientific Reports
Extracellular vesicles (EVs) are released during the storage of red blood cell (RBC) concentrates and might play adverse or beneficial… Continue reading Storage conditions determine the characteristics of red blood cell derived extracellular vesicles
2022 / Scientific Reports
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of extracellular amyloid-beta peptides (Aβ) resulting in senile plaques… Continue reading Administration of mucuna beans (Mucuna pruriences (L.) DC. var. utilis) improves cognition and neuropathology of 3 × Tg-AD mice
2021 / ADVANCED MATERIALS INTERFACES
Tissue reconstruction has an unmet need for soft active scaffolds that enable gentle loading with regeneration-directing bioactive components by soaking… Continue reading An Inverse Shape-Memory Hydrogel Scaffold Switching Upon Cooling in a Tissue-Tolerated Temperature Range
2021 / Macro Molecular Rapid Communications
ABC-type triblock copolymers are a rising platform especially for oligonucleotide delivery as they offer an additional functionality besides the anyhow… Continue reading Cross-Linkable Polyion Complex Micelles from Polypept(o)ide-Based ABC-Triblock Copolymers for siRNA Delivery
2021 / ChemBioChem
The vanillyl-alcohol oxidase (VAO) family is a rich source of biocatalysts for the oxidative bioconversion of phenolic compounds. Through genome… Continue reading Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis
2021 / microbial biotechnology
Treatment with rumen fluid improves methane production from non-degradable lignocellulosic biomass during subsequent methane fermentation; however, the kinetics of xylanases… Continue reading Shifts in xylanases and the microbial community associated with xylan biodegradation during treatment with rumen fluid
2022 / FASEB Journal
N-Linked glycosylation and O-linked N-acetylglucosamine (O-GlcNAc) are important protein post-translational modifications that are orchestrated by a diverse set of gene… Continue reading O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
2021 / Food Science + Technology
Freeze-drying is a good alternative means of obtaining fruit products, with a significant amount of thermolabile bioactive compounds. Despite the… Continue reading Impact of freeze-drying shelf temperature on the bioactive compounds, physical properties and sensory evaluation of a product based on orange juice
2022 / Nature Communications
Although computational simulation-based natural product syntheses are in their initial stages of development, this concept can potentially become an indispensable… Continue reading Computation-guided asymmetric total syntheses of resveratrol dimers
2022 / Scientific Reports
A method to produce hybrid organotitanias, both as thin films and suspensions, showing excellent photocatalyic activity in the degradation of… Continue reading Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2
2021 / Molecuar Systems Biology
The co-catabolism of multiple host-derived carbon substrates is required by Mycobacterium tuberculosis (Mtb) to successfully sustain a tuberculosis infection. However,… Continue reading Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis
2021 / ChemBioChem
Photocaged compounds are applied for implementing precise, optochemical control of gene expression in bacteria. To broaden the scope of UV-light-responsive… Continue reading Optochemical Control of Bacterial Gene Expression: Novel Photocaged Compounds for Different Promoter Systems
