Among the molecular mechanisms of adaptation in biology, enzyme functional diversification is indispensable. By allowing organisms to expand their catalytic …
Continue reading “Evolution of Enzyme Functionality in the Flavin-Containing Monooxygenases”
Carlos Morillo
March 16, 2023
Carlos Morillo
March 16, 2023
Domino Knoevenagel-cyclization reactions of 2H-chromene and chroman derivatives containing o-formylaryl amine or ether side-chain was carried out to produce four …
Continue reading “Multifaceted Domino Knoevenagel-Cyclization Reactions; Four Movements for 2H-Chromenes and Chromans”
Carlos Morillo
March 16, 2023
Sensing small biomolecules in biofluids remains challenging for many optical chemosensors based on supramolecular host-guest interactions due to adverse interplays …
Continue reading “A supramolecular cucurbit[8]uril-based rotaxane chemosensor for the optical tryptophan detection in human serum and urine”
Carlos Morillo
February 8, 2023
The development of circularly polarized luminescence (CPL)-active materials with both large luminescence dissymmetry factor (glum) and high emission efficiency continues …
Continue reading “Opposing effects of clozapine and brexpiprazole on β-aminoisobutyric acid: Pathophysiology of antipsychotics-induced weight gain”
Carlos Morillo
February 8, 2023
This study quantified the nutritional components and imidazole dipeptide levels of commercially available meats (beef, pork, and duck), and their …
Continue reading “Composition and taste of beef, pork, and duck meat and bioregulatory functions of imidazole dipeptides in meat”
Carlos Morillo
February 8, 2023
Carlos Morillo
February 8, 2023
The demethylation of Nε-methyllysine residues on histones by Jumonji-C lysine demethylases (JmjC-KDMs) has been established. A subset of JmjC-KDMs has …
Continue reading “The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation”
Carlos Morillo
February 8, 2023
Mediated extracellular electron transfer (EET) might be a great vehicle to connect microbial bioprocesses with electrochemical control in stirred-tank bioreactors. …
Continue reading “Screening of natural phenazine producers for electroactivity in bioelectrochemical systems”
Carlos Morillo
January 31, 2023
The discrimination of enantiomers by natural receptors is a well-established phenomenon. In contrast the number of synthetic receptors with the …
Continue reading “Preferential molecular recognition of heterochiral guests within a cyclophane receptor”
Carlos Morillo
January 31, 2023
Incommensurate double-wall carbon nanotubes give rise to unique stereochemistry originating from twisted stacks of hexagon arrays. However, atomic-level studies on …
Continue reading “Target-oriented design of helical nanotube molecules for rolled incommensurate bilayers”
Carlos Morillo
December 2, 2022
Nicotinamide adenine dinucleotide (NAD) is an essential cofactor for numerous enzymes involved in energy metabolism. Because decreasing NAD levels is …
Continue reading “Porcine placental extract increase the cellular NAD levels in human epidermal keratinocytes”
Carlos Morillo
November 14, 2022
Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, …
Continue reading “First Occurrence of Megastigmane Glucosides in a Plant of Retama Genus”
Carlos Morillo
October 19, 2022
We report on the triplet sensitization of the intramolecular Photo-Dehydro-Diels-Alder (PDDA) reaction of two diaryl suberates bearing methyl propiolate chromophors. …
Continue reading “Triplet Sensitized Photo-Dehydro-Diels-Alder Reaction”
Carlos Morillo
October 19, 2022
Highest global cancer incidence of female breast cancer is a matter of great concern. HER2-positive breast cancers have high mortality …
Continue reading “Synthesis and comparative evaluation of 177Lu-labeled PEG and non-PEG variant peptides as HER2-targeting probes”
Carlos Morillo
October 3, 2022
Sub/supercritical fluid chromatography (SFC) is a green separation technique that has been used to separate a wide variety of compounds …
Continue reading “Insights into enantioselective separations of ionic metal complexes by sub/supercritical fluid chromatography”
Danielle Bridges
September 26, 2022
Carlos Morillo
September 12, 2022
A long-standing question regarding carbonaceous chondrites (CCs) is how the CCs’ organics were sourced and converted before and after the …
Continue reading “Geoelectrochemistry-driven alteration of amino acids to derivative organics in carbonaceous chondrite parent bodies”
Carlos Morillo
August 30, 2022
Photocatalysis process is a promising technology for environmental remediation. In the continuous search of new heterogeneous photocatalysts, metal–organic frameworks (MOFs) …
Continue reading “Ti-based robust MOFs in the combined photocatalytic degradation of emerging organic contaminants”
Carlos Morillo
August 30, 2022
Hollow polymer particles are widely used in various industries as coatings and thermal insulation materials. The encapsulation capabilities of various …
Continue reading “Systematic study on fabrication of hollow poly(vinyl cinnamate) particles by particulate interfacial photocrosslinking”
Carlos Morillo
July 21, 2022