2021 / Nature Communications
Introns of human transfer RNA precursors (pre-tRNAs) are excised by the tRNA splicing endonuclease TSEN in complex with the RNA …
2021 / Nature Communications
Canine parvovirus type II (CPV-2) infection induces canine parvoviral enteritis (CPE), which in turn promotes sepsis and systemic inflammatory response …
2021 / Processes 2021
Liquefaction of waste lignocellulosic biomass is a viable technology for replacing fossil fuels and meeting sustainable development goals. In this …
2021 / Nature Communications
Mutations in the type 1 ryanodine receptor (RyR1), a Ca2+ release channel in skeletal muscle, hyperactivate the channel to cause …
2021 / Enzyme and microbial technology
The ene reductases (ERs) from the old yellow enzymes (OYEs) family have the ability to reduce activated alkenes to generate …
2021 / Scientific reports
Thermophilic biohydrogen production by dark fermentation from a mixture (1:1) of C5 (arabinose) and C6 (glucose) sugars, present in lignocellulosic …
2021 / Scientific reports
Herpes simplex virus is among the most prevalent sexually transmitted infections. Acyclovir is a potent, selective inhibitor of herpes viruses …
Continue reading “Pseudoboehmite as a drug delivery system for acyclovir”
2021 / Environmental Science and Pollution Research
Sampling, separation, detection, and characterization of microplastics (MPs) dispersed in natural water bodies and ecosystems is a challenging and critical …
2021 / Nature Communications
Biological membranes play pivotal roles in the cellular activities. Transmembrane proteins are the central molecules that conduct membrane-mediated biochemical functions …
Continue reading “A synthetic ion channel with anisotropic ligand response”
2021 / Scientific Report
Attachment of polysaccharide carriers is increasingly being used to achieve precision delivery and improved effectiveness of protein and peptide drugs. …
2021 / Scientific Report
Cell-penetrating peptides have important therapeutic applications in drug delivery, but the variety of known cell-penetrating peptides is still limited. With …
2021 / Scientific Report
Temperature-responsive chromatography using thermoresponsive polymers is innovative and can control analyte retention via column temperature. Analyte elution behavior in this …
2021 / Scientific Report
In patients with chronic kidney disease, skeletal muscle dysfunction is associated with mortality. Uremic sarcopenia is caused by ageing, malnutrition, …
2021 / Scientific Report
We developed a novel method for production of no-carrier-added (n.c.a.) [188, 189, 191Pt]PtIICl42− from an Ir target material, and then …
2021 / Scientific Report
Two-pore channel 2 (TPC2) resides in endolysosomal membranes but also in lysosome-related organelles such as the melanin producing melanosomes. Gain-of-function …
2021 / MDPI
In this work, the use of fluorescent molecular rotors such as 9-(2,2-dicyanovinyl)julolidine (DCVJ) and 2,3-bis(4-(phenyl(4-(1,2,2-triphenylvinyl) phenyl)amino)phenyl)fumaronitrile (TPETPAFN) was proposed for …
2021 / Nature Communications, 12, Article number: 1530 (2021)
De novo protein design is advancing rapidly. However, most designs are for single states. Here we report a de novo …
Continue reading “Structural resolution of switchable states of a de novo peptide assembly”
2021 / Nature Communications
The design of efficient chiral catalysts is of crucial importance since it allows generating enantiomerically pure compounds. Tremendous efforts have …
2021 / Translational Psychiatry
d-Serine acts as a co-agonist of N-methyl-d-aspartate receptors (NMDAR) which appear overactivated in AD, while d-aspartate is a modulatory molecule …
2021 / Bioscience, Biotechnology, and Biochemistry
Corydalis ambigua (Japanese name, Ezoengosaku) flowers bloom with blue to purplish petals in early spring in Hokkaido prefecture. In this …
