Development and Validation of LC Method for the Simultaneous Estimation of Rosuvastatin Calcium and Olmesartan Medoxomil in Pharmaceutical Dosage Form

2014 / International Journal of ChemTech Research

A simple, fast, and precise reverse phase, isocratic HPLC method was developed for the separation and quantification of Rosuvastatin calcium …

DJ Tognarelli

A Validated Stability Indicating RP-HPLC Method for Nabumetone, Identification and Characterization of Forced Degradation Products of Nabumetone Using LC-MS/MS

2013 / Asian Journal of Chemistry

The objective of the present study was to report the stability of novel non-steroidal antiinflammatory drug (NSAID), nabumetone based on …

DJ Tognarelli

DEVELOPMENT AND VALIDATION OF LC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ROSIGLITAZONE MALEATE AND GLIMEPIRIDE IN PHARMACEUTICAL DOSAGE FORM

2012 / Malaysian Journal of Pharmaceutical Sciences

A simple, precise and accurate high performance liquid chromatography (HPLC) method was developed for simultaneous quantitative determination of rosiglitazone maleate …

DJ Tognarelli

DEVELOPMENT AND VALIDATION OF A RP – LC METHOD FOR DISSOLUTION TEST OF EFAVIRENZ TABLETS AND ITS APPLICATION TO DRUG QUALITY CONTROL STUDIES

2013 / Asian Journal of Pharmaceutical and Clinical Research

A liquid chromatographic method is developed to evaluate a new dissolution profile of Efavirenz in tablet dosage form. The dissolution …

DJ Tognarelli

Development and Validation of Rapid HPLC Method for Determination of Doxofylline in Bulk Drug and Pharmaceutical Dosage Forms

2009 / Journal of Analytical Chemistry

A simple, selective, rapid, and economical reversed phase high performance liquid chromatogra phy(RPHPLC) method for the determination of doxofylline in …

DJ Tognarelli

Development, Validation and Statistical Correlation of RP–LC Methods for Determination of Atazanavir Sulfate in Capsule Dosage Form

2012 / Journal of Chemistry

To study the effective therapeutic bioavailability of Atazanavir Sulfate (ATV), administered singly or in combination with Ritonavir, a cost effective …

DJ Tognarelli

A validated stability indicating RP-HPLC method for valganciclovir, identification and characterization of forced degradation products of valganciclovir using LC-MS/MS

2014 / Acta Chromatographica

The objective of the present study was to report the stability of novel antiviral drug, valganciclovir based on the information …

DJ Tognarelli

Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns

2018 / Methods, Volume 146, 15 August 2018, Pages 39-45

Protein G can be a valuable binding agent for antibodies and immunoglobulins in methods such as immunosensors, chromatographic-based immunoassays, and …

DJ Tognarelli

Enantiomeric impurity analysis using circular dichroism spectroscopy with United States Pharmacopeia liquid chromatographic methods

2018 / Journal of Pharmaceutical and Biomedical Analysis

Over 300 chiral drug substances lack official United States Pharmacopeia (USP) methods for the enantiomeric purity determination. Because enantiomeric analysis …

Leah Pandiscia, PhD