expression CMS Single Quadrapole Mass Spectrometer Detector
The expression CMS range of compact single quadrapole mass spectrometers for small molecule analysis. The CMS can be interfaced with HPLC or SFC for analytical to preparative scale separations. ChromNAV chromatography Data system, includes integrated control for selecting measurement parameters and executing measurement with timed event control for switching polarity and mass range. TIC, EIC and SIM can all be used to monitor chromatograms and to trigger fraction collection for selective fractionation.
| Specification | cms-E | cms-S | cms-L |
|---|---|---|---|
| Ion Source | ESI, APCI, or APCI/ASAP (direct analysis probe) | ||
| API interface | orthogonal ion sampling from heated capillary – allows for small single turbo pump (Patents pending) | ||
| Flow rate range | 10 µL/min to 1 mL/min ESI; 10 µL/min to 2 mL/min APCI | ||
| Polarity | Positive & Negative ion switching in single analysis | ||
| Polarity Switching Speed | 50 ms | ||
| m/z Range | 80 to 800 m/z | 10 to 1,200 m/z | 10 to 2,000 m/z |
| Acquisition speed | 10,000 m/z units sec-1 (compatible with UHPLC) | ||
| Resolution | 0.5-0.7 m/z units (FWHM) at 1000 m/z units sec-1 over entire acquisition range | ||
| SIM sensitivity | 10 pg Reserpine (FIA – 5µL sample injection volume at 100 µL/min) 100:1 S/N (RMS) with SIM of m/z 609.28 | ||
| Accuracy | ± 0.1 m/z units over entire acquisition range | ||
| Dynamic Range | 4.5 orders of magnitude | ||