Multi-stimuli-responsive chiral organogels based on peptide derivatives

July 28, 2017

Title

Multi-stimuli-responsive chiral organogels based on peptide derivatives

Author

Chang-Wei Liu, Ming Su, Xue-Liang Li, Teng Xue, Na Liu, Jun Yin, Yuan-Yuan Zhu, Zong-Quan Wu

Year

2015

Journal

Soft Matter

Abstract

A series of chiral aryl amide compounds bearing peptide pendants have been investigated as low molecular weight gelators. A mechanistic study reveals that complementary hydrogen bonding from peptide pendants is the main driving force for the formation of organogels. This new class of organogels can exhibit multi-stimuli-responsive behavior upon applying (1) thermal, (2) pH, (3) enantiomeric purity, and (4) fluoride anion stimuli. Enantiomeric purity as a new external stimulus displays sensitive stimuli-responsiveness; only 0.02 equiv. of the enantiomer can completely disassemble the gel aggregate. They will serve as excellent smart materials with potential applications in chiral sensors, recognition, and separation.

Instrument

J-1500

Keywords

Circular dichroism, Stereochemistry, Materials