Antioxidant farnesylated hydroquinones from Ganoderma capense

July 28, 2017

Title

Antioxidant farnesylated hydroquinones from Ganoderma capense

Author

Xingrong Peng, Lei Li, Xia Wang, Guolei Zhu, Zhongrong Li, Minghua Qiu

Year

2016

Journal

Fitoterapia

Abstract

Phytochemical investigation of the fruiting bodies of Ganoderma capense led to isolation of eight aromatic meroterpenoids (1–8). Ganocapensins A and B (1, 2) possessed a thirteen-membered and a fourteen-membered ether rings, respectively. The structures of new isolates including absolute configuration were elucidated on the basis of extensive spectroscopic technologies and Mosher's method. All isolated compounds showed significant antioxidant effects with IC50 values ranging from 6.00 ± 0.11 to 8.20 ± 0.30 μg/ml in the DPPH radical scavenging assay.

Instrument

J-815

Keywords

Circular dichroism, Absolute configuration, Medicinal