Title
Photoactive g-C3N4 Nanosheets for Light-Induced Suppression of Alzheimer’s β-Amyloid Aggregation and Toxicity
Author
You Jung Chung, Byung Il Lee, Jong Wan Ko, Chan Beum Park
Year
2016
Journal
Advanced Healthcare Materials
Abstract
Graphitic carbon nitride (g-C3N4) has a suppressive capability toward Alzheimer's Aβ aggregation under light-illumination. Photoinduced electrons of g-C3N4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Aβ aggregation. Fe doping of g-C3N4 frameworks results in enhanced optical properties and even stronger inhibition of Aβ aggregation.
Instrument
J-???
Keywords
Circular dichroism, Secondary structure, Aggregation, Nanostructures, Materials, Biochemistry