Title
Indole Alkaloids from the Leaves of Nauclea officinalis
Author
Long Fan, Cheng-Hui Liao, Qiang-Rong Kang, Kai Zheng, Ying-Chun Jiang, Zhen-Dan He
Year
2016
Journal
Molecules
Abstract
Three new indole alkaloids, named naucleamide G (1), and nauclealomide B and C (5 and 6), were isolated from the n-BuOH-soluble fraction of an EtOH extract of the leaves of Nauclea officinalis, together with three known alkaloids, paratunamide C (2), paratunamide D (3) and paratunamide A (4). The structures with absolute configurations of the new compounds were identified on the basis of 1D and 2D NMR, HRESIMS, acid hydrolysis and quantum chemical circular dichroism (CD) calculation. According to the structures of isolated indole alkaloids, their plausible biosynthetic pathway was deduced.
Full Article
Instrument
J-810
Keywords
Circular dichroism, Absolute configuration, Medicinal, Natural products