Title
Enantioselective Detection of D- and L-Phenylalanine Using Optically Active Polyaniline
Author
Edel M. Sheridan, Carmel B. Breslin
Year
2005
Journal
Electroanalysis
Abstract
Chiral conducting polyaniline, which was prepared electrochemically from (+) and (−) camphorsulfonic acid, was utilized for the enantiomeric detection of phenylalanine in neutral phosphate buffer solution. Following electropolymerization the polymer films were dedoped in aqueous ammonia and subsequently shown to maintain their chiral character. The electrochemical window for this polymer was determined to be between 0.2 V and 0.8 V (vs. SCE) and enantiomeric discrimination between L- and D-phenylalanine was seen with the application of differential pulse voltammetry. The (+) chiral polymer is shown to behave as an enantiomeric detector for the D enantiomer producing a peak in the voltammogram at ca. 0.7 V (vs. SCE) while the inverse is true for the (−) polymer, which detects theL enantiomer.
Instrument
J-810
Keywords
Circular dichroism, Stereochemistry, Polymers