Title
Effect of the metal ion on the enantioselectivity and linkage isomerization of thiosemicarbazone helicates
Author
Ana M. González-Noya, María J. Romero, Vanesa Suárez, Sandra Fernández-Fariña, Marcelino Maneiro, Emilio Martínez-Núñez, Guillermo Zaragoza, Rosa Pedrido
Year
2017
Journal
Chemistry A European Journal
Abstract
The effect of the metal ion and ligand design on the enantioselectivity and linkage isomerization of neutral cobalt and zinc bisthiosemicarbazone metallohelicates has been investigated in this work. The electrochemical synthesis has afforded the enantioselective formation of chiral pure cobalt helicates, and the isomer of a single enantiomer has been crystallized as only product for the cobalt methyl-substituted thiosemicarbazone helicate. Interestingly linkage isomers have been isolated from zinc ethyl-substituted thiosemicarbazone helicate enantiomers for the first time. The co-existence of these isomers has been evaluated from the point of view of both experimental results and computational calculations.
Instrument
J-1100
Keywords
Circular dichroism, Stereochemistry, Inorganic chemistry, Coordination chemistry