Ceylonins G–I: spongian diterpenes from the marine sponge Spongia ceylonensis

By Ahmed H. El-Desoky, Hikaru KatoSachiko Tsukamoto

July 28, 2017

  • Year

  • Technique

  • Industry

Title

Ceylonins G–I: spongian diterpenes from the marine sponge Spongia ceylonensis

Author

Ahmed H. El-Desoky, Hikaru KatoSachiko Tsukamoto

Year

2017

Journal

Journal of Natural Medicines

Abstract

Three new spongian diterpenes, ceylonins G–I (1–3), were isolated from the marine sponge Spongia ceylonensis collected in Indonesia, together with five known spongian diterpenes (4–8). Only 4 inhibited USP7 with an IC50 value of 8.2 lM.

Full Article

https://link.springer.com/article/10.1007/s11418-017-1087-4

Instrument

J-820

Keywords

Circular dichroism, Absolute configuration, Natural products, Pharmaceutical