Title
Synthesis of block copolymers using end-functionalized polyacetylenes as macroinitiators
Author
Masashi Shiotsuki, Kei Takahashi, Jesus Rodriguez Castanon, Fumio Sanda
Year
2018
Journal
Polymer Chemistry
Abstract
Polyacetylenes substituted with phenyl, N-tert-butoxycarbonyl-L-valine 4-anilide, and (S)-1-(acetoxy)ethyl groups with number-average molecular weights ranging from 3800 to 13 500 were synthesized by the polymerization of the corresponding acetylene monomers using [{1,1′-bis(diphenylphosphino)ferrocene}PdBr(C6H4-o-CH2OH)] as a catalyst. L-Lactide and γ-benzyl-L-glutamate N-carboxyanhydride were polymerized using the polyacetylenes as macroinitiators to obtain the block copolymers, some of which formed chiral secondary structures. A block copolymer consisting of helically twisted polyacetylene and α-helical peptide was successfully synthesized for the first time.
Instrument
J-820
Keywords
Circular dichroism, Cotton effect, Stereochemistry, Secondary structure, Polymers