Multifunctional carbon dot for lifetime thermal sensing, nucleolus imaging and antialgal activity

October 11, 2018

Title

Multifunctional carbon dot for lifetime thermal sensing, nucleolus imaging and antialgal activity

Author

Hao Li, Mengling Zhang, Yuxiang Song, Huibo Wang, Chang'an Liu, Yijun Fu, Hui Huang, Yang Liu, Zhenhui Kang

Year

2018

Journal

Journal of Materials Chemistry B

Abstract

Multifunctional carbon dots (CDs) with lifetime thermal sensing, nucleolus imaging, and antialgal activity properties were synthesized directly from ascorbic acid aqueous solution by a one-step electrochemical method at room temperature. The as-prepared CDs are responsive to temperature and exhibit an accurate linear response of fluorescence intensity vs. temperature (20–100 °C). These CDs can enter a cell and nucleolus, adsorb on the nucleic acids (DNA and RNA) and the fluorescence intensity of CDs is increased by the adsorption of nucleic acids. In addition, the CDs can inhibit the activity of RuBisCO in Anabaena sp., leading to reducing the growth of Anabaena sp. All these properties make the CDs serve as effective fluorescence-based nanothermometers, nucleolus probes, and antialgal agents.

Instrument

J-815

Keywords

Circular dichroism, Secondary structure, Chemical stability, Biochemistry, Materials