Title
Vibrational Circular Dichroism System Equipped with Quantum Cascade Laser for Microscopic Scanning
Author
Hisako Sato, Masaru Shimizu, Keisuke Watanabe, Jun Yoshida, Izuru Kawamura, and Jun Koshoubu
Year
2021
Journal
Chemistry Letters, 2021, Vol.50, No.8
Abstract
A vibrational circular dichroism (VCD) system capable of microscopic scanning was developed. An intense infrared light from a quantum cascade laser was focused using two BaF2 lenses and passed through a pinhole of 0.1 mmϕ. A solid sample mounted on an automatic stage was scanned two-dimensionally with a spatial resolution of 100 µm in the wavenumber range of 1500–1740 cm−1. The feasibility of the system was validated by reproducing the authentic VCD peaks assigned to the amide I and II bands of a dipeptide, Gly-d-Leu.
Full Article
Instrument
VCD
Keywords
VCD, microscopic scanning