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Ultra High-Speed Analysis of Alkylphenones by UHPLC

By Satoko Suzuki

Introduction

Alkylphenones are often used for evaluating HPLC systems because of their reasonable retention times on ODS columns and easy separation with a water/acetonitrile mobile phase.

This report outlines the ultra-high speed analysis of alkylphenones analysis by Ultra High-performance Liquid Chromatography (UHPLC) using with a PDA detector (high-speed data acquisition of 100 spectra/sec).

Experimental

Keywords

032001X

Results

Figure 1 3D chromatogram of an alkylphenone standard mixture containing 9 components. All of the alkylphenones were successfully separated and detected within 12 seconds.

Figure 1. 3D Chromatogram of standard alkylphenones.

1: Acetanilide, 2: Acetophenone,3: Propiophenone, 4: Butyrophenone, 5: Benzophenone, 6: Valerophenone, 7: Hexanophenone, 8: Heptanophenone, 9: Octanophenone.

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