Ultra High-Speed Analysis of Alkylphenones by UHPLC
August 18, 2022
Introduction
Alkylphenones are often used for evaluating HPLC systems because of their reasonable retention times on ODS columns and easy separation with a water/acetonitrile mobile phase.
This report outlines the ultra-high speed analysis of alkylphenones analysis by Ultra High-performance Liquid Chromatography (UHPLC) using with a PDA detector (high-speed data acquisition of 100 spectra/sec).
Experimental
Results
Figure 1 3D chromatogram of an alkylphenone standard mixture containing 9 components. All of the alkylphenones were successfully separated and detected within 12 seconds.
1: Acetanilide, 2: Acetophenone,3: Propiophenone, 4: Butyrophenone, 5: Benzophenone, 6: Valerophenone, 7: Hexanophenone, 8: Heptanophenone, 9: Octanophenone.
