Self-assembling nanostructured peptide gels are promising materials for sensing, drug delivery, and energy harvesting. Of particular interest are short diphenylalanine… Continue reading Thermally-controlled spherical peptide gel architectures prepared using the pH switch method
Carlos Morillo
February 24, 2023
A representative Co(II) based single ion magnet (SIM) with N2O2 donor set and distorted pseudo-tetrahedral geometry has been synthesized and… Continue reading Static and Dynamic Magnetic Properties of a Co(II)-Complex with N2O2 Donor Set – A Theoretical and Experimental Study
Carlos Morillo
February 24, 2023
UFMylation involves the covalent modification of substrate proteins with UFM1 (Ubiquitin-fold modifier 1) and is important for maintaining ER homeostasis.… Continue reading Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy
Carlos Morillo
February 24, 2023
Post-synthetic modification (PSM) is an effective approach for tailored functionalization of metal-organic architectures, but its generalizability remains challenging. Herein we… Continue reading Tailor-Made PdnL2n Metal-Organic Cages via Covalent Post-Synthetic Modification
Carlos Morillo
February 24, 2023
We herein investigated chiroptical activities of pyrene clusters incorporated within a DNA duplex. Three pyrene derivatives were prepared on D-threoninol… Continue reading Orientational Control of Circularly Polarized Luminescence from Pyrene Clusters using a DNA Scaffold.
Carlos Morillo
February 24, 2023
Inspired by biological helices (e.g., DNA), artificial helical polymers have attracted intense attention. However, precise synthesis of one-handed helices from… Continue reading Visible Helicity Induction and Memory in Polyallene toward Circularly Polarized Luminescence, Helicity Discrimination, and Enantiomer Separation
Carlos Morillo
February 24, 2023
Due to burgeoning interest in the pharmaceutical industry in exploiting optically active α-aminoboronic derivatives as bioisosteres of α-amino acid derivatives,… Continue reading Enantioselective Synthesis of α-Aminoboronic Acid Derivatives via Copper-Catalyzed N-Alkylation
Carlos Morillo
February 24, 2023
Rhodobacter (Rba.) capsulatus has been a favored model for studies of all aspects of bacterial photosynthesis. This purple phototroph contains… Continue reading Rhodobacter capsulatus forms a compact crescent-shaped LH1–RC photocomplex
Carlos Morillo
February 24, 2023
The phenomenon of protein aggregation is associated with a wide range of human diseases. Our knowledge of the aggregation behaviour… Continue reading Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
Carlos Morillo
February 24, 2023
Nanochannels in laminated graphene oxide nanosheets featuring confined mass transport have attracted interest in multiple research fields. The use of… Continue reading Deformation constraints of graphene oxide nanochannels under reverse osmosis
Carlos Morillo
February 24, 2023
Emulsions are critical across a broad spectrum of industries. Unfortunately, emulsification requires a significant driving force for droplet dispersion. Here,… Continue reading Interfacial solute flux promotes emulsification at the water|oil interface
Carlos Morillo
February 24, 2023
Thousands of genetic variants in protein-coding genes have been linked to disease. However, the functional impact of most variants is… Continue reading Aberrant phase separation and nucleolar dysfunction in rare genetic diseases
Carlos Morillo
February 24, 2023
Light chain (AL) amyloidosis is a debilitating disease in which mutant antibody light chains (LC), secreted by aberrant plasma cell… Continue reading A constant domain mutation in a patient-derived antibody light chain reveals principles of AL amyloidosis
Carlos Morillo
February 24, 2023
To better understand how amino acid sequence encodes protein structure, we engineered mutational pathways that connect three common folds (3α,… Continue reading Design and characterization of a protein fold switching network
Carlos Morillo
February 24, 2023
The RNA binding protein TDP-43 forms cytoplasmic inclusions via its C-terminal prion-like domain in several neurodegenerative diseases. Aberrant TDP-43 aggregation… Continue reading Metamorphism in TDP-43 prion-like domain determines chaperone recognition
Carlos Morillo
February 24, 2023
1,3a,6a-Triazapentalene (TAP) is a compact fluorescent chromophore whose fluorescence properties vary greatly depending on the substituents on the TAP ring.… Continue reading 1,3a,6a-Triazapentalene derivatives as photo-induced cytotoxic small fluorescent dyes
Carlos Morillo
February 24, 2023
Carlos Morillo
February 24, 2023
The SNARE complex assembles from vesicular Synaptobrevin-2 as well as Syntaxin-1 and SNAP25 both anchored to the presynaptic membrane. It… Continue reading Mass spectrometry uncovers intermediates and off-pathway complexes for SNARE complex assembly
Carlos Morillo
February 24, 2023
Carlos Morillo
February 24, 2023
Functionalization of graphene is one of the most important fundamental technologies in a wide variety of fields including industry and… Continue reading Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis
Carlos Morillo
February 24, 2023