AntiSMASH analysis of genome DNA of Streptomyces CPCC 204980, a soil isolate with potent antibacterial activity, revealed a gene cluster for polycyclic… Continue reading Cytotoxic and Antibacterial Cervinomycins B1–4 from a Streptomyces Species
Leah Pandiscia, PhD
November 13, 2019
The detailed characterizations of the binding interactions between food additive tartrazine (TZ) and β-lactoglobulin (β-LG) have been investigated through spectroscopic… Continue reading Curious Results in the Prospective Binding Interactions of the Food Additive Tartrazine with β-Lactoglobulin
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Ten structurally related homoleptic complexes, including three new compounds, were synthesized: five [VIVO(L-H)2] and five [VVO(OCH3)(L-H)2] compounds, where L–H =… Continue reading Exploring oxidovanadium(iv) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents
Leah Pandiscia, PhD
November 13, 2019
Polymer‐stabilized cholesteric liquid crystal (PSCLC) films with broadband reflection based on two‐step photopolymerization are fabricated. Owing to the helical twisting… Continue reading Effect of Monomer Composition on the Performance of Polymer‐Stabilized Liquid Crystals with Two‐Step Photopolymerization
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Common experimental approaches for characterizing structural conversion processes such as protein folding and self-assembly do not report on all aspects… Continue reading Application of millisecond time-resolved solid state NMR to the kinetics and mechanism of melittin self-assembly
Leah Pandiscia, PhD
November 13, 2019
Many peptides aggregate into insoluble β-sheet rich amyloid fibrils. Some of these aggregation processes are linked to age-related diseases, such… Continue reading The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide’s Secondary Structure
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Ruthenium–arene complexes are a unique class of organometallic compounds that have been shown to have prominent therapeutic potencies. Here, we… Continue reading Covalent versus Noncovalent Binding of Ruthenium η6‐p‐Cymene Complexes to Zinc‐Finger Protein NCp7
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Sphingosine kinase 1 (SphK1) catalyzes the conversion of sphingosine to sphingosine-1-phosphate that acts as a bioactive signalling molecule, and regulates… Continue reading Functional implications of pH-induced conformational changes in the Sphingosine kinase 1
Leah Pandiscia, PhD
November 13, 2019
The reaction of N-(2,4-dinitrophenyl)pyridinium chloride (salt(Cl−)) with lithium bis(trifluoromethanesulfonyl)imide (TFSI−LI+) and lithium bis(nonafluorobutanesulfonyl)imide (NFSI−LI+) resulted in the anion exchange between Cl− and… Continue reading Synthesis and chemical properties of conjugated polymers with bis(trifluoromethanesulfonyl)imide and bis(nonafluorobutanesulfonyl)imide anions
Leah Pandiscia, PhD
November 13, 2019
The glycolytic enzyme enolase of Staphylococcus aureus is a highly conserved enzyme which binds to human plasminogen thereby aiding the infection process.… Continue reading Effect of ions and inhibitors on the catalytic activity and structural stability of S. aureus enolase
Leah Pandiscia, PhD
November 13, 2019
Gold nanoparticles (GNPs) of different sizes and shapes have been investigated extensively for their therapeutic potential against several diseases including cancer. However,… Continue reading Perturbation of tubulin structure by stellate gold nanoparticles retards MDA-MB-231 breast cancer cell viability
Leah Pandiscia, PhD
November 13, 2019
Nα-acetylation is a universal protein modification related to a wide range of physiological processes in eukaryotes and prokaryotes. RimI, an Nα-acetyltransferase… Continue reading Biophysical and functional characterizations of recombinant RimI acetyltransferase from Mycobacterium tuberculosis
Leah Pandiscia, PhD
November 13, 2019
Protein disulfide isomerase (PDI) is a redox-dependent protein with oxidoreductase and chaperone activities. It is a U-shaped protein with an abb′xa′ structural… Continue reading Stability and Conformational Resilience of Protein Disulfide Isomerase
Leah Pandiscia, PhD
November 13, 2019
Three different applications of travelling heating zone reactor (THZR) chromatography for the downstream processing of monoclonal antibodies (mAbs) are described.… Continue reading Integrated system for temperature-controlled fast protein liquid chromatography. III. Continuous downstream processing of monoclonal antibodies
Leah Pandiscia, PhD
November 13, 2019
The potential use of polyphenols to improve the functional characteristics of dairy products has gained much attention. However, the effects… Continue reading Binding characteristics of polyphenols as milk plasmin inhibitors
Leah Pandiscia, PhD
November 13, 2019
Although urine cytology and cystoscopy are current gold standard methods in diagnosis and surveillance of Bladder cancer (BC), they have… Continue reading In silico design and in vitro characterization of a recombinant antigen for specific recognition of NMP22
Leah Pandiscia, PhD
November 13, 2019