Several strikingly different aerobic and anaerobic pathways of nicotinate breakdown are extant in bacteria. Here, through reverse genetics and analytical… Continue reading A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans
Carlos Morillo
August 16, 2022
The malaria parasite Plasmodium invades a host erythrocyte, multiplies within a parasitophorous vacuole (PV) and then ruptures the PV and… Continue reading Maturation and substrate processing topography of the Plasmodium falciparum invasion/egress protease plasmepsin X
Carlos Morillo
August 16, 2022
Artificial, synthetic chaperones have attracted much attention in biomedical research due to their ability to control the folding of proteins… Continue reading Multifunctional synthetic nano-chaperone for peptide folding and intracellular delivery
Carlos Morillo
August 16, 2022
Embedding metal-halide perovskite particles within an insulating host matrix has proven to be an effective strategy for revealing the outstanding… Continue reading Mechanochemistry-driven engineering of 0D/3D heterostructure for designing highly luminescent Cs–Pb–Br perovskites
Carlos Morillo
August 16, 2022
Recombinant spider silk proteins (spidroins) have multiple potential applications in development of novel biomaterials, but their multimodal and aggregation-prone nature… Continue reading Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform
Carlos Morillo
August 16, 2022
Thousands of natural products are derived from the fused cyclopentane-pyran molecular scaffold nepetalactol. These natural products are used in an… Continue reading Biocatalytic routes to stereo-divergent iridoids
Carlos Morillo
August 16, 2022
G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small… Continue reading Development of a novel light-up probe for detection of G-quadruplexes in stress granules
Carlos Morillo
August 16, 2022
The human pathogen Mycobacterium tuberculosis requires a P1B-ATPase metal exporter, CtpC (Rv3270), for resistance to zinc poisoning. Here, we show… Continue reading Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms
Carlos Morillo
August 16, 2022
Peptidomimetic polymers have attracted increasing interest because of the advantages of facile synthesis, high molecular tunability, resistance to degradation, and… Continue reading Intrinsically fluorescent polyureas toward conformation-assisted metamorphosis, discoloration and intracellular drug delivery
Carlos Morillo
August 16, 2022
Partial melting in the continental crust may play a critical role on the behavior of continents during collision. However, the… Continue reading Crustal melting in orogenic belts revealed by eclogite thermal properties
Carlos Morillo
August 16, 2022
Insulin-like growth factors (IGFs) have pleiotropic roles in embryonic and postnatal growth and differentiation. Most serum IGFs are bound in… Continue reading Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex
Carlos Morillo
August 16, 2022
SiGe is a promising anode material for replacing graphite in next generation thin-film batteries owing to its high theoretical charge/discharge… Continue reading Si1–xGex anode synthesis on plastic films for flexible rechargeable batteries
Carlos Morillo
August 16, 2022
A simple quantitative reverse phase high performance liquid chromatographic (RP-HPLC) method has been developed and validated for assay determination of… Continue reading Analytical method validation for assay determination of cannabidiol and tetrahydrocannabinol in hemp oil infused products by RP-HPLC
Carlos Morillo
August 16, 2022
This paper reports a new hydrogel extraction technique for detecting blue fluorescent substances in plant leaves. These blue fluorescent substances… Continue reading Hydrogel-extraction technique for non-invasive detection of blue fluorescent substances in plant leaves
Carlos Morillo
August 16, 2022
The customized design of micro-/nanomotors represents one of the main research topics in the field of micro-/nanomotors; however, the effects… Continue reading Facet nanoarchitectonics of visible-light driven Ag3PO4 photocatalytic micromotors: Tuning motion for biofilm eradication
Carlos Morillo
August 16, 2022
Allergies have become a rising health problem, where plentiful substances can trigger IgE-mediated allergies in humans. While profilins are considered… Continue reading A native IgE in complex with profilin provides insights into allergen recognition and cross-reactivity
Carlos Morillo
August 16, 2022
Carlos Morillo
August 16, 2022
Carlos Morillo
August 16, 2022
Since liquid–liquid phase separation (LLPS) of proteins is governed by their intrinsically disordered regions (IDRs), it can be controlled by… Continue reading Rational peptide design for regulating liquid–liquid phase separation on the basis of residue–residue contact energy
Carlos Morillo
August 16, 2022
Proteomic, cellular and biochemical analysis of the stress protein NUPR1 reveals that it binds to PARP1 into the nucleus and… Continue reading NUPR1 protects against hyperPARylation-dependent cell death
Carlos Morillo
August 16, 2022