Found 9617 Results / Page 33 of 481
2022 / Nature Communications
All living organisms have the ability to sense nutrient levels to coordinate cellular metabolism. Despite the importance of nutrient-sensing pathways… Continue reading O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine
2022 / Nature Communications
The RTX (repeats-in-toxin) domain of the bacterial toxin adenylate cyclase (CyaA) contains five RTX blocks (RTX-i to RTX-v) and its… Continue reading Templated folding of the RTX domain of the bacterial toxin adenylate cyclase revealed by single molecule force spectroscopy
2022 / Nature Communications
Intimately connected to the rule of life, chirality remains a long-time fascination in biology, chemistry, physics and materials science. Chiral… Continue reading Chiral emergence in multistep hierarchical assembly of achiral conjugated polymers
2022 / Scientific Reports
Biocementation using enzyme induced carbonate precipitation (EICP) process has become an innovative method for soil improvement. One of the major… Continue reading Polymer-assisted enzyme induced carbonate precipitation for non-ammonia emission soil stabilization
2022 / Scientific Reports
Growing antimicrobial resistance has prompted researchers to identify new natural molecules with antimicrobial potential. In this perspective, attention has been… Continue reading Antimicrobial properties of chitosan from different developmental stages of the bioconverter insect Hermetia illucens
2022 / Scientific Reports
The protein HSF-1 is the controlling transcription factor of the heat-shock response (HSR). Its binding to the heat-shock elements (HSEs)… Continue reading Binding of the HSF-1 DNA-binding domain to multimeric C. elegans consensus HSEs is guided by cooperative interactions
2022 / Scientific Reports
Anticancer strategies aimed at inhibiting Complex I of the mitochondrial respiratory chain are increasingly being attempted in solid tumors, as… Continue reading Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer
2022 / Scientific Reports
Calcium (Ca2+) is well known as a second messenger in eukaryotes, where Ca2+ signaling controls life-sustaining cellular processes. Although bacteria… Continue reading EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa
2022 / Scientific Reports
Lead phthalocyanine (PbPc) is well known to be used as a good near-infrared (NIR) light absorber for organic solar cells… Continue reading Unraveling the reasons behind lead phthalocyanine acting as a good absorber for near-infrared sensitive devices
2022 / Scientific Reports
Magnetic hyperthermia (MHT) is in the spotlight of nanomedical research for the treatment of cancer employing magnetic iron oxide nanoparticles… Continue reading Iron oxide nanoflowers encapsulated in thermosensitive fluorescent liposomes for hyperthermia treatment of lung adenocarcinoma
2022 / Scientific Reports
We have faced the preparation of fully water-soluble fluorescent peptide substrate with long-term environmental stability (in solution more than 35… Continue reading The role of polymeric chains as a protective environment for improving the stability and efficiency of fluorogenic peptide substrates
2022 / Scientific Reports
Insulin balls, localized insulin amyloids formed at the site of repeated insulin injections in patients with diabetes, cause poor glycemic… Continue reading Differences in interaction lead to the formation of different types of insulin amyloid
2022 / Scientific Reports
Skeletal stem cells (SSCs, or mesenchymal stromal cells typically referred to as mesenchymal stem cells from the bone marrow) are… Continue reading Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation
2022 / Euro JOC
The base induced activation of β-naphthol toward the electrophilic aromatic substitution has been used for the synthesis of the unprecedent… Continue reading A Vibrational and Electronic Circular Dichroism Study of Chiral Seleno Compounds Prepared from a Novel Naphthol based Diselenide.
2022 / Food Science
Medium-chain triacylglycerols (MCTs), including caprylic acid (C8), a mixture of caprylic acid and capric acid (C8+C10), and high-MCT coconut oil… Continue reading Physicochemical properties and volatile formation mechanism of medium-chain triacylglycerols during heating
2022 / PROTEIN SCIENCE
Evolution minimizes the number of highly conserved amino acid residues in proteins to ensure evolutionary robustness and adaptability. The roles… Continue reading The roles of highly conserved, non-catalytic residues in class A β-lactamases
2021 / Nucleic Acids Research ,Volume 49, Issue 14, 20 August 2021, Pages 7856–7869
The MYCN gene encodes the transcription factor N-Myc, a driver of neuroblastoma (NB). Targeting G-quadruplexes (G4s) with small molecules is… Continue reading Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene
2022 / EurJOC
Cadmium porphyrin cage compounds Cd1 and 113Cd1 have been synthesized from the free base porphyrin cage derivative H21 and Cd(OAc)2 ⋅ 2… Continue reading 113Cd as a Probe in NMR Studies of Allosteric Host-Guest-Ligand Complexes of Porphyrin Cage Compounds
2022 / Protein science
The conformational landscape of a protein is constantly expanded by genetic variations that have a minimal impact on the function(s)… Continue reading Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase
2022 / ADVANCED MATERIALS
Laser-induced forward transfer (LIFT) is a rapid laser-patterning technique for high-throughput combinatorial synthesis directly on glass slides. A lack of… Continue reading Automated Laser-Transfer Synthesis of High-Density Microarrays for Infectious Disease Screening
