Flavonoids are dietary intakes which are bestowed with several health benefits. The most studied property of flavonoids is their antioxidant… Continue reading Correlation of binding efficacies of DNA to flavonoids and their induced cellular damage
Leah Pandiscia, PhD
July 28, 2017
Reducing the promiscuous tropism of native adenovirus by using fiberless adenovirus is advantageous towards its use as a gene therapy… Continue reading Identification of Excipients for Stabilizing Fiberless Adenovirus as Biopharmaceuticals
Leah Pandiscia, PhD
July 28, 2017
Eleven new sesquiterpenoids, including eight cadinane-type sesquiterpenoids, Ganodermanol A–H (1–8), and three eudesmane-type sesquiterpenoids, Ganodermanol I–K (9–11), together with three… Continue reading Sesquiterpenoids from the cultured mycelia of Ganoderma capense
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Selective configuration control of plasmonic nanostructures using either top-down or bottom-up approaches has remained challenging in the field of active… Continue reading Selective control of reconfigurable chiral plasmonic metamolecules
Leah Pandiscia, PhD
July 28, 2017
Complex coacervate core micelles (C3Ms) are colloidal structures useful for encapsulation of biomacromolecules. We previously demonstrated that enhanced green fluorescent… Continue reading Encapsulation into complex coacervate core micelles promotes EGFP dimerization
Leah Pandiscia, PhD
July 28, 2017
We describe a novel label-free and signal-on electrochemical DNA sensing platform via proximity hybridization triggered hemin/G-quadruplex formation based on the… Continue reading Proximity hybridization triggered hemin/G-quadruplex formation for construction a label-free and signal-on electrochemical DNA sensor
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
We showed that the Taylor Dispersion Analysis (TDA) is a fast and easy to use method for the study of… Continue reading Denaturation of proteins by surfactants studied by the Taylor dispersion analysis
Leah Pandiscia, PhD
July 28, 2017
Constructing optically active helical polymer based nanomaterials without using expensive and limited chirally helical polymers has been becoming an extremely… Continue reading Helix-Sense-Selective Co-precipitation for Preparing Optically Active Helical Polymer Nanoparticles/Graphene Oxide Hybrid Nanocomposites
Leah Pandiscia, PhD
July 28, 2017
A new lactone, 5R-methyl-3-heptatriacontyl-2(5H)-furanone (1), was isolated from the twigs of Cinnamomum cassia. The structure of the new compound was established… Continue reading A New Lactone from the Twigs of Cinnamomum cassia
Leah Pandiscia, PhD
July 28, 2017
Horseradish peroxidase was reconstituted with cobalt tetradehydrocorrin, rHRP(Co(TDHC)), as a structural analog of cobalamin coordinated with an imidazolate-like His residue,… Continue reading Cobalt tetradehydrocorrins coordinated by imidazolate-like histidine in the heme pocket of horseradish peroxidase
Leah Pandiscia, PhD
July 28, 2017
526-residue FUS functions to self-assemble into reversible droplets/hydrogels, which could be further solidified into pathological fibrils. FUS is intrinsically prone… Continue reading RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously selfassembles into amyloid fibrils
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Interactions of a natural stilbene compound, resveratrol with two DNA sequences containing AATT/TTAA segments have been studied. Resveratrol is found… Continue reading Binding of resveratrol to the minor groove of DNA sequences with AATT and TTAA segments induces differential stability
Leah Pandiscia, PhD
July 28, 2017
In Rhodospirillum rubrum, the maturation of Carbon Monoxide Dehydrogenase (CODH) requires three accessory proteins, CooC, CooT and CooJ, dedicated to… Continue reading The CO dehydrogenase accessory protein CooT is a novel nickel-binding protein
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
DNA sequences that are guanine-rich have received considerable attention due to their potential to fold into a secondary, four-stranded DNA… Continue reading A Biochemical and Biophysical Model of G-quadruplex DNA Recognition by Positive Coactivator of Transcription 4
Leah Pandiscia, PhD
July 28, 2017