Studying the mode of interaction between small molecules and DNA has received much attention in recent years, as many drugs… Continue reading Interaction of capsaicin with calf thymus DNA: A multi-spectroscopic and molecular modelling study
Leah Pandiscia, PhD
July 28, 2017
The unusual (R) configuration previously assigned (with seemingly undoubted evidence) to purpuroin A and nakirodin A was disproved by synthesis.… Continue reading Synthesis of purpuroine A, nakirodin A and MDN-0104: The hidden puzzles and risk of error in their configurational assignments
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
G-quadruplexes (G4s) have become important drug targets to regulate gene expression and telomere maintenance. Many studies on G4 ligand binding… Continue reading What stoichiometries determined by mass spectrometry reveal about the ligand binding mode to G-quadruplex nucleic acids ☆
Leah Pandiscia, PhD
July 28, 2017
The application of gene delivery materials has been mainly focused on mammalian cells while rarely extended to plant engineering. Cationic… Continue reading Gene delivery into isolated Arabidopsis thaliana protoplasts and intact leaves using cationic, α-helical polypeptide
Leah Pandiscia, PhD
July 28, 2017
Self-assembly using imine condensation chemistry in combination with metal coordination is becoming one of the leading strategies for the preparation… Continue reading Second Generation tris(2-pyridylmethyl)amine Zinc Complexes as Probes for Enantiomeric Excess Determination of Amino Acids
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
This paper reports a new ratiometric probe for the detection of adenosine 5′-triphosphate (ATP) that is based on the binding-induced… Continue reading A new FRET-based ratiometric probe for fluorescence and colorimetric analyses of adenosine 5′-triphosphate
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Light chain (AL) amyloidosis is a lethal disease characterized by the deposition of the immunoglobulin light chain into amyloid fibrils,… Continue reading Differences in Protein Concentration Dependence for Nucleation and Elongation in Light Chain Amyloid Formation
Leah Pandiscia, PhD
July 28, 2017
Porins form trimers in the outer membrane and help transport nutrients and waste products across the bacterial cell membrane. Porin… Continue reading Characterization of Salmonella typhi OmpC and OmpF porins engineered with HIV-gp41 epitope on the surface loops
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
G-Quadruplex (G4) structures of a human telomeric 24-mer (5′-TTAGGGTTAGGGTTAGGGTTAGGG-3′) sequence (Tel24) stabilized by sodium and potassium ions have been assessed… Continue reading Assessment of human telomeric G-quadruplex structures using surface-enhanced Raman spectroscopy
Leah Pandiscia, PhD
July 28, 2017
Structural control of the self-assembled lipid membrane is an important and interesting challenge, both for revealing the mechanisms behind biological… Continue reading Reversible Vesicle-to-Disk Transitions of Liposomes Induced by Self-Assembly of Water-Soluble Porphyrins
Leah Pandiscia, PhD
July 28, 2017
A facile, highly selective biosensor was used for ATP quantitative analysis. Here we introduced two hairpins as matrix. While Exo… Continue reading Free-Labelled Fluorescent Method for ATP Detection Assisted by T4 DNA Ligase
Leah Pandiscia, PhD
July 28, 2017
In the food industry, biocatalysts provide ecofriendly procedures to accomplish biochemical reactions with high specificity in moderate conditions. In this… Continue reading Production of the Renewable Extremophile Lipase; Valuable Biocatalyst with Potential Usage in Food Industry
Leah Pandiscia, PhD
July 28, 2017
Lycium chinense Mill. is a deciduous shrub in the Solanaceae family that is known for its fruits (Lycii fructus) and root… Continue reading Nine new compounds from the root bark of Lycium chinense and their α-glucosidase inhibitory activity
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017