Alkaloids from Galanthus fosteri

July 28, 2017

Title

Alkaloids from Galanthus fosteri

Author

Ahmet Emir, Ceren Emir, Buket Bozkurt, Mustafa Ali Onur, Jaume Bastid, Nehir Unver Somer

Year

2016

Journal

Phytochemistry Letters

Abstract

Three new alkaloids, oxoincartine, 3,11-O-diacetyl-9-O-demethylmaritidine and 11-O-acetyl-9-O-demethylmaritidine together with seven known compounds namely, incartine, galanthamine, galanthine, 9-O-methylpseudolycorine, N,O-dimethylnorbelladine, hordenine and vittatine were isolated from Galanthus fosteri Baker (Amaryllidaceae). Their structures were elucidated by spectroscopic analyses (UV, IR, MS, CD and 1D/2D NMR). Cholinesterase inhibitory activity potentials of the compounds were also determined.

Instrument

J-810

Keywords

Circular dichroism, Absolute configuration, Natural products, Pharmaceutical