Anti-piroplasma activity of 2-methylbutane galloyl glycosides from Saxifraga spinulosa

September 27, 2021

Title

Anti-piroplasma activity of 2-methylbutane galloyl glycosides from Saxifraga spinulosa

Author

Batsukh Odonbayar

Year

2021

Journal

Phytochemistry Letters

Abstract

Five new galloyl glucosides of 2-C-methyl-D-erythriol (1–4) and homogentisic acid (5) were isolated from the aerial parts of Saxifraga spinulosa. The structures of the new compounds were elucidated by spectroscopic methods. The absolute configuration was determined using alkaline hydrolysis on their ester bond. The parasitic growth inhibitory activities were evaluated against Babesia bigemina, B. bovis, B. caballi, and Theileria equi, which cause protozoan diseases of livestock, and the results indicated that the presence of the galloyl moiety is important and aglycone moieties also affect the activities.

Instrument

P-2300

Keywords

Saxifraga spinulosa, aglycone, moieties