Title
Ca2+ ion sensing by a piperidin-4-one derivative and the effect of β-cyclodextrin complexation on the sensing
Author
M. Sumithra, R. Sivaraj, G. Tamil Selvan, P. Mosae Selvakumar, Israel V.M.V. Enoch
Year
2017
Journal
Journal of Luminescence
Abstract
In this paper, we report the turn-on fluorescence based Ca2+ ion sensing by an anthracene piperidin-4-one derivative. The compound is obtained using a simple two step synthesis. The compound is characterized using NMR and mass spectral methods. The host-guest complex formation of the compound with β-cyclodextrin is prepared and characterized using fluorescence and 2D ROESY spectroscopy. The compound forms the inclusion complex with a 1:1 stoichiometry. The structure of the host-guest complex is proposed. The Ca2+ ion selectivity of the compound in its free form and cyclodextrin-bound forms are studied. In both the forms, the piperidin-4-one derivative senses Ca2+and in the case of the cyclodextrin encapsulated form it shows a better competitive binding of Ca2+ in the presence of other metal ions.
Instrument
FP-8300
Keywords
Fluorescence, Ligand binding, Sensors, Chemical stability, Materials