Chemical constituents from the fruiting bodies of Cryptoporus volvatus

July 28, 2017

Title

Chemical constituents from the fruiting bodies of Cryptoporus volvatus

Author

Junchi Wang, Guangzhi Li, Na Lv, Li Gao, Li Cao, Liangang Shen, Jianyong Si

Year

2016

Journal

Archives of Pharmaceutical Research

Abstract

New drimane-type sesquiterpene cryptoporol A (1), cryptoporic acid derivative 6′-cryptoporic acid E methyl ester (2), and pseudouridine derivative cryptoporine A (3), as well as a known ergosterol 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4), were isolated from a 90 % alcohol extract of the fruiting bodies of Cryptoporus volvatus. The structures of these compounds were established by spectroscopic analysis and circular dichroism. 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4) exhibited antiviral activity against porcine reproductive and respiratory syndrome virus, and all compounds showed weak antioxidant activities.

Instrument

J-815

Keywords

Circular dichroism, Stereochemistry, Absolute configuration, Pharmaceutical