Chemical constituents from the fruiting bodies of Cryptoporus volvatus
Junchi Wang, Guangzhi Li, Na Lv, Li Gao, Li Cao, Liangang Shen, Jianyong Si
Archives of Pharmaceutical Research
New drimane-type sesquiterpene cryptoporol A (1), cryptoporic acid derivative 6′-cryptoporic acid E methyl ester (2), and pseudouridine derivative cryptoporine A (3), as well as a known ergosterol 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4), were isolated from a 90 % alcohol extract of the fruiting bodies of Cryptoporus volvatus. The structures of these compounds were established by spectroscopic analysis and circular dichroism. 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (4) exhibited antiviral activity against porcine reproductive and respiratory syndrome virus, and all compounds showed weak antioxidant activities.
Circular dichroism, Stereochemistry, Absolute configuration, Pharmaceutical