Chemical constituents from the whole plants of Pilea cavaleriei Levl subsp. cavaleriei
Yong Zhou, Ling-Yu Li, Heng-Chun Ren, Ri-Dong Qin, Qin Li, Peng-Fei Tu, Gui-Fang Dou, Qing-Ying Zhang, Hong Liang
Three new sesquiterpene glycosides (1–3), three new glycerol glycosides (4–6), two new alkaloids (7–8), together with seven known compounds (9–15) all of which were isolated from the genus Pilea for the first time, were isolated from the whole plants of Pilea cavaleriei Levl subsp. cavaleriei. Their structures were determined by extensive spectroscopic techniques and chemical methods. The cytotoxic activity of the isolated compounds was evaluated against four cancer cell lines, and none of the tested compounds caused a significant reduction of the cell number.
Circular dichroism, Absolute configuration, Stereochemistry, Natural products, Pharmaceutical