Title
Chemical constituents of the root bark of Erythrina droogmansiana
Author
Kibrom Gebreheiwot Bedane, Souvik Kusari, Anke Bullach, Ishmael B. Masesane, Shetonde O. Mihigo, Michael Spiteller, Runner R.T. Majinda
Year
2017
Journal
Phytochemistry Letters
Abstract
Two new compounds namely 7,4′-dihydroxy-2′-methoxy-3′-(3-methylbut-2-enyl)isoflavanone (1) and 5,7,3′-trihydroxy-8-(3-methylbut-2-enyl)-[6′′,6′′-dimethylpyrano(2′′,3′′:4′,5′)]isoflavone (4) were isolated from the root bark of Erythrina droogmansiana together with eight known compounds. Their structures were elucidated on the basis of spectroscopic analyses (1D- and 2D-NMR and ESI-HRMS) and by comparison with literature data. In addition, the correct 13C NMR of 5,7,2′,4′-tertahydroxy-8,5′-di-(3-metylbut-2-enyl)isoflavone (6) was assigned. The DPPH free radical scavenging properties of the isolated compounds were evaluated. Compounds 4–7 showed weak to moderate DPPH free radical scavenging activities.
Instrument
J-715
Keywords
Circular dichroism, Absolute configuration, Natural products, Agricultural and environmental