Chiral Recognition of 2-Alkylalcohols with Magnetic Circular Dichroism Measurement of Porphyrin J-Aggregate on Silica Gel Plate

July 28, 2017

Title

Chiral Recognition of 2-Alkylalcohols with Magnetic Circular Dichroism Measurement of Porphyrin J-Aggregate on Silica Gel Plate

Author

Hitoshi Watarai, Yuriko Kurahashi

Year

2016

Journal

Analytical Chemistry

Abstract

Simple chiral recognition method of 2-alkylalcohols on a silica gel plate was proposed by using the induced circular dichroism (ICD) of J-aggregates of diprotonated tetraphenylporphyrin and magnetic circular dichroism (MCD) spectrometry. To the silica gel on a glass slide including a chiral 2-alkylalcohol and 4 M sulfuric acid, the porphyrin in toluene was added and mixed. Then, the glass slide was used for in situ MCD measurement. The observed ICD spectra could recognize well the chirality of the alcohols and the ICD intensity normalized by the MCD intensity of the J-aggregate correlated linearly to the amount of the chiral alcohols in the silica gel.

Instrument

J-820

Keywords

Circular dichroism, Magnetic circular dichroism, Stereochemistry