Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus

July 28, 2017

Title

Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus

Author

Qing Li, Ying-Na He, Xiao-Wei Shi, Li-Ying Kang, Li-Ying Niu, Xin-Guo Wang, Wei Feng

Year

2016

Journal

Fitoterapia

Abstract

Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part ofClerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro.

Instrument

J-815

Keywords

Circular dichroism, Absolute configuration, Pharmaceutical