Computer-assisted retention prediction of polycyclic aromatic hydrocarbons in supercritical fluid chromatography using carbon dioxide as the mobile phase

October 1, 2018

Title

Computer-assisted retention prediction of polycyclic aromatic hydrocarbons in supercritical fluid chromatography using carbon dioxide as the mobile phase

Author

K. Jinno, M. Kuwajima

Year

1987

Journal

Chromatographia, September 1987, Volume 23, Issue 9, pp 631–638

Abstract

The dependence of the capacity factor of polycyclic aromatic hydrocarbons on column temperature and on the density of the mobile phase in supercritical-fluid chromatography was investigated using carbon dioxide as the mobile phase. Logarithmic capacity factors of polycyclic aromatic hydrocarbons were obtained as a linear function of the reciprocal column temperature at a constant molar volume of carbon dioxide.

The application of the Retention Prediction System to supercritical-fluid chromatography is demonstrated: one can predict the retention of polycyclic aromatic hydrocarbons using equations including column temperature, density and the physico-chemical properties of the solutes as the parameters.

Instrument

SFC

Keywords

Supercritical fluid chromatography, Carbon dioxide, Polycyclic aromatics, Retention prediction