Title
Hyperhexanone A, a crucial intermediate from bicyclo[3.3.1]- to cyclohexanone monocyclic-polycyclic polyprenylated acylphloroglucinols
Author
Hucheng Zhu, Chunmei Chen, Jing Yang, Dongyan Li, Jinwen Zhang, Yi Guo, Jianping Wang, Zengwei Luo, Yongbo Xue, Yonghui Zhang
Year
2016
Journal
Tetrahedron
Abstract
Hyperhexanones A (1) and B (2), two novel polycyclic polyprenylated acylphloroglucinol (PPAPs) derivatives, were isolated from Hypericum sampsonii. Compound 1 possesses a novel 1,2-seco-bicyclo[3.3.1]-PPAP skeleton, which represents a crucial intermediate from bicyclo[3.3.1]-PPAPs to the peculiar cyclohexanone monocyclic-PPAPs (CM-PPAPs). A plausible biogenetic pathway was proposed to discuss the origins of the CM-PPAPs.
Instrument
J-810
Keywords
Circular dichroism, Absolute configuration, Medicinal, Natural products